Francesca F Norman1, Jorge Rojas-Marcos2, José-Manuel Hermida-Donate2, Begoña Monge-Maillo3, Jose Antonio Perez-Molina3, Rogelio López-Vélez3. 1. Infectious Diseases Department, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain Tropical Medicine and Clinical Parasitology Unit, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain ffnorman@gmail.com. 2. Infectious Diseases Department, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain. 3. Infectious Diseases Department, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain Tropical Medicine and Clinical Parasitology Unit, Ramón y Cajal Hospital, IRYCIS, Madrid, Spain.
Abstract
BACKGROUND: Splenic infarction is a well recognised complication of malaria that has been infrequently reported in the literature. METHODS: A review was performed to describe the spectrum of characteristics associated with this complication. RESULTS: Most patients presented with fever, left upper quadrant pain and/or splenomegaly, but no specific symptoms or signs appear to predict underlying infarction. The majority of cases reported were associated with autochthonous Plasmodium vivax infections, whereas cases reported in travellers were mostly due to P. falciparum acquired in Africa. CONCLUSION: Identification of infarction may allow specific recommendations for management, and associated complications such as splenic rupture should be excluded. Outcome is generally favourable and conservative management is the preferred option.
BACKGROUND:Splenic infarction is a well recognised complication of malaria that has been infrequently reported in the literature. METHODS: A review was performed to describe the spectrum of characteristics associated with this complication. RESULTS: Most patients presented with fever, left upper quadrant pain and/or splenomegaly, but no specific symptoms or signs appear to predict underlying infarction. The majority of cases reported were associated with autochthonous Plasmodium vivax infections, whereas cases reported in travellers were mostly due to P. falciparum acquired in Africa. CONCLUSION: Identification of infarction may allow specific recommendations for management, and associated complications such as splenic rupture should be excluded. Outcome is generally favourable and conservative management is the preferred option.
Authors: Norinne Lacerda-Queiroz; Nicolas Riteau; Richard T Eastman; Kevin W Bock; Marlene S Orandle; Ian N Moore; Alan Sher; Carole A Long; Dragana Jankovic; Xin-Zhuan Su Journal: Sci Rep Date: 2017-09-05 Impact factor: 4.379
Authors: Marion Louvois; Loïc Simon; Christelle Pomares; Pierre-Yves Jeandel; Elisa Demonchy; Michel Carles; Pascal Delaunay; Johan Courjon Journal: Front Med (Lausanne) Date: 2022-01-17