Literature DB >> 24942852

A Hg(II)-mediated "signal-on" electrochemical glutathione sensor.

Hamid R Lotfi Zadeh Zhad1, Rebecca Y Lai.   

Abstract

We report the design and fabrication of a DNA-based electrochemical sensor for detection of glutathione. Sensor signaling relies on glutathione's ability to chelate mercury Hg(II), displacing it from the thymine-Hg(II)-thymine complex formed between the surface-immobilized DNA probes. Our results show that this sensor is sensitive and selective enough to be employed in saliva.

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Year:  2014        PMID: 24942852     DOI: 10.1039/c4cc03329a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Bioinspired Assemblies and Plasmonic Interfaces for Electrochemical Biosensing.

Authors:  Samuel S Hinman; Quan Cheng
Journal:  J Electroanal Chem (Lausanne)       Date:  2016-05-27       Impact factor: 4.464

Review 2.  Beyond Sensitive and Selective Electrochemical Biosensors: Towards Continuous, Real-Time, Antibiofouling and Calibration-Free Devices.

Authors:  Susana Campuzano; María Pedrero; Maria Gamella; Verónica Serafín; Paloma Yáñez-Sedeño; José Manuel Pingarrón
Journal:  Sensors (Basel)       Date:  2020-06-16       Impact factor: 3.576

  2 in total

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