| Literature DB >> 24942852 |
Hamid R Lotfi Zadeh Zhad1, Rebecca Y Lai.
Abstract
We report the design and fabrication of a DNA-based electrochemical sensor for detection of glutathione. Sensor signaling relies on glutathione's ability to chelate mercury Hg(II), displacing it from the thymine-Hg(II)-thymine complex formed between the surface-immobilized DNA probes. Our results show that this sensor is sensitive and selective enough to be employed in saliva.Entities:
Mesh:
Substances:
Year: 2014 PMID: 24942852 DOI: 10.1039/c4cc03329a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222