Literature DB >> 24938590

Colorectal cancer of the elderly.

Lukejohn W Day1, Fernando Velayos.   

Abstract

OPINION STATEMENT: Colorectal cancer (CRC) disproportionately affects the elderly. Older age is a strong risk factor for both the development of precancerous adenomas and CRC, thus raising the issue of screening and surveillance in older patients. However, screening and surveillance decisions in the elderly can be complex and challenging. Elderly patients are a diverse and heterogeneous group and special considerations such as co-morbid medical conditions, functional status, and cognitive ability play a role in one's decisions regarding the utility of screening and surveillance. Such considerations also play a role in factors related to screening modalities, such as colonoscopy, as well as CRC treatment options and regimens. This review addresses many of the unique factors associated with CRC of the elderly and critically examines many of the controversies and challenges surrounding CRC in older patients.

Entities:  

Year:  2014        PMID: 24938590     DOI: 10.1007/s11938-014-0021-z

Source DB:  PubMed          Journal:  Curr Treat Options Gastroenterol        ISSN: 1092-8472


  66 in total

Review 1.  Split dosing of bowel preparations for colonoscopy: an analysis of its efficacy, safety, and tolerability.

Authors:  Lawrence B Cohen
Journal:  Gastrointest Endosc       Date:  2010-07-01       Impact factor: 9.427

2.  The time course and effect on serum electrolytes of oral sodium phosphates solution in healthy male and female volunteers.

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Journal:  Can J Clin Pharmacol       Date:  2007-11-01

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Journal:  J Clin Gastroenterol       Date:  2005 Nov-Dec       Impact factor: 3.062

4.  Predictive factors for detecting colorectal carcinomas in surveillance colonoscopy after colorectal cancer surgery.

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5.  Serrated lesions of the colorectum: review and recommendations from an expert panel.

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Journal:  Am J Gastroenterol       Date:  2012-06-19       Impact factor: 10.864

6.  Outcomes of a 5-year follow-up of patients with sessile serrated adenomas.

Authors:  Anouar Teriaky; David K Driman; Nilesh Chande
Journal:  Scand J Gastroenterol       Date:  2012-01-10       Impact factor: 2.423

7.  Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients with node-positive colon cancer.

Authors:  Vijaya Sundararajan; Nandita Mitra; Judith S Jacobson; Victor R Grann; Daniel F Heitjan; Alfred I Neugut
Journal:  Ann Intern Med       Date:  2002-03-05       Impact factor: 25.391

8.  Five-year follow-up after radical surgery for colorectal cancer. Results of a prospective randomized trial.

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Journal:  Arch Surg       Date:  1995-10

9.  Electrolyte disorders following oral sodium phosphate administration for bowel cleansing in elderly patients.

Authors:  Yichayaou Beloosesky; Josef Grinblat; Avraham Weiss; Boris Grosman; Uzi Gafter; Avry Chagnac
Journal:  Arch Intern Med       Date:  2003-04-14

10.  The impact of colorectal cancer screening in a veteran hospital population.

Authors:  John Trombold; Russell W Farmer; Michael McCafferty
Journal:  Am Surg       Date:  2013-03       Impact factor: 0.688

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  5 in total

1.  Downregulated Tim-3 expression is responsible for the incidence and development of colorectal cancer.

Authors:  Ping Zhang; Yan Wang; Xue-Rong Liu; Shi-Ru Hong; Jian Yao
Journal:  Oncol Lett       Date:  2018-05-11       Impact factor: 2.967

2.  Upregulation of spondin-2 predicts poor survival of colorectal carcinoma patients.

Authors:  Qian Zhang; Xiao-Qing Wang; Jie Wang; Shu-Jian Cui; Xiao-Min Lou; Bing Yan; Jie Qiao; Ying-Hua Jiang; Li-Jun Zhang; Peng-Yuan Yang; Feng Liu
Journal:  Oncotarget       Date:  2015-06-20

3.  Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line.

Authors:  Hai-Juan Xiao; Jun-Ming Hou; Jin Li; Yuan Wang; Cheng-Gong Zhang; Jing-Dong He
Journal:  Cancer Cell Int       Date:  2018-01-04       Impact factor: 5.722

4.  Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.

Authors:  Xiao-Qing Wang; Zu-Xiong Tang; Dong Yu; Shu-Jian Cui; Ying-Hua Jiang; Qian Zhang; Jie Wang; Peng-Yuan Yang; Feng Liu
Journal:  Oncotarget       Date:  2016-02-23

5.  Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors.

Authors:  Xinqiang Zhu; Kui Yi; Daorong Hou; Hailong Huang; Xuetong Jiang; Xiaohong Shi; Chungen Xing
Journal:  Med Sci Monit       Date:  2020-07-23
  5 in total

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