Literature DB >> 24937455

MDS is a stem cell disorder after all.

Siddhartha Jaiswal1, Benjamin L Ebert2.   

Abstract

Myelodysplastic syndrome (MDS) has long been presumed to be a stem cell disorder, but rigorous formal proof has been lacking. In this issue of Cancer Cell, Woll and colleagues demonstrate that driver mutations occurring in MDS definitively occur in cells with a stem cell phenotype.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24937455     DOI： 10.1016/j.ccr.2014.06.001

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  7 in total

1.  Blockade of BCL-2 proteins efficiently induces apoptosis in progenitor cells of high-risk myelodysplastic syndromes patients.

Authors:  S Jilg; V Reidel; C Müller-Thomas; J König; J Schauwecker; U Höckendorf; C Huberle; O Gorka; B Schmidt; R Burgkart; J Ruland; H-J Kolb; C Peschel; R A J Oostendorp; K S Götze; P J Jost
Journal:  Leukemia       Date:  2015-07-08       Impact factor: 11.528

2.  Myelodysplastic syndrome can propagate from the multipotent progenitor compartment.

Authors:  Kevin Rouault-Pierre; Alexander E Smith; Syed A Mian; Irene Pizzitola; Austin G Kulasekararaj; Ghulam J Mufti; Dominique Bonnet
Journal:  Haematologica       Date:  2016-10-06       Impact factor: 9.941

Review 3.  Detection of Solid Tumor Molecular Residual Disease (MRD) Using Circulating Tumor DNA (ctDNA).

Authors:  Re-I Chin; Kevin Chen; Abul Usmani; Chanelle Chua; Peter K Harris; Michael S Binkley; Tej D Azad; Jonathan C Dudley; Aadel A Chaudhuri
Journal:  Mol Diagn Ther       Date:  2019-06       Impact factor: 4.074

4.  Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.

Authors:  Giulio Genovese; Anna K Kähler; Robert E Handsaker; Johan Lindberg; Samuel A Rose; Samuel F Bakhoum; Kimberly Chambert; Eran Mick; Benjamin M Neale; Menachem Fromer; Shaun M Purcell; Oscar Svantesson; Mikael Landén; Martin Höglund; Sören Lehmann; Stacey B Gabriel; Jennifer L Moran; Eric S Lander; Patrick F Sullivan; Pamela Sklar; Henrik Grönberg; Christina M Hultman; Steven A McCarroll
Journal:  N Engl J Med       Date:  2014-11-26       Impact factor: 91.245

Review 5.  Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish.

Authors:  Anne L Robertson; Serine Avagyan; John M Gansner; Leonard I Zon
Journal:  FEBS Lett       Date:  2016-09-25       Impact factor: 4.124

Review 6.  Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies.

Authors:  Hironori Harada; Yuka Harada
Journal:  Cancer Sci       Date:  2015-02-25       Impact factor: 6.716

7.  Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells.

Authors:  Huafeng Wang; Jie Sun; Bin Zhang; Dandan Zhao; Hongyan Tong; Herman Wu; Xia Li; Yingwan Luo; Dan Dong; Yiyi Yao; Tinisha McDonald; Anthony S Stein; Monzr M Al Malki; Flavia Pichiorri; Nadia Carlesso; Ya-Huei Kuo; Guido Marcucci; Ling Li; Jie Jin
Journal:  Clin Transl Med       Date:  2021-10
  7 in total

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