Literature DB >> 24936332

Technical and dosimetric aspects of the total skin electron beam technique implemented at Heidelberg University Hospital.

Frank W Hensley1, Gerald Major1, Carolin Edel2, Henrik Hauswald1, Marc Bischof1.   

Abstract

AIM: To give a technical description and present the dosimetric proporties of the total skin electron beam technique implemented at Heidelberg University Hospital.
BACKGROUND: Techniques used for total skin electron beam irradiation were developed as early as in the 1960s to 1980s and have, since then, hardly changed. However, new measurements of the established methods allow deeper insight into the dose distributions and reasons for possible deviations from uniform dose.
MATERIALS AND METHODS: The TSEI technique applied at Heidelberg University Hospital since 1992 consists of irradiating the patient with a superposition of two beams of low energy electrons at gantry angles of 72° and 108° while he is rotating in a standing position on a turntable at 370 cm distance from the accelerator. The energy of the electron beam is degraded to 3.9 MeV by passing through an attenuator of 6 mm of Perspex. A recent re-measurement of the dose distribution is presented using modern dosimetry tools like a linear array of ionization chambers in combination with established methods like thermoluminescent detectors and film dosimetry.
RESULTS: The measurements show a strong dependence of dose uniformity on details of the setup like gantry angles.
CONCLUSIONS: Dose uniformity of -4/+8% to the majority of the patient's skin can be achieved, however, for the described rotational technique overdoses up to more than 20% in small regions seem unavoidable.

Entities:  

Keywords:  Dosimetry; Electrons; Total skin therapy; X-ray contamination

Year:  2013        PMID: 24936332      PMCID: PMC4054981          DOI: 10.1016/j.rpor.2013.07.002

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  21 in total

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Journal:  Med Phys       Date:  1998-06       Impact factor: 4.071

6.  First application of total skin electron beam irradiation in Greece: setup, measurements and dosimetry.

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Journal:  Phys Med       Date:  2011-04-22       Impact factor: 2.685

7.  Total skin electron beam therapy for cutaneous T-cell lymphoma: a nationwide cohort study from Denmark.

Authors:  Lise M Lindahl; Maria R Kamstrup; Peter M Petersen; Johan Wirén; Morten Fenger-Grøn; Robert Gniadecki; Lars Iversen; Lena Specht
Journal:  Acta Oncol       Date:  2011-07-08       Impact factor: 4.089

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Journal:  Int J Radiat Oncol Biol Phys       Date:  1977 Sep-Oct       Impact factor: 7.038

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Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-09-30       Impact factor: 7.038

10.  Total skin electron beam therapy as palliative treatment for cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia.

Authors:  Henrik Hauswald; Felix Zwicker; Nathalie Rochet; Matthias Uhl; Frank Hensley; Jürgen Debus; Klaus Herfarth; Marc Bischof
Journal:  Radiat Oncol       Date:  2012-07-29       Impact factor: 3.481

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  6 in total

1.  Total skin electron irradiation-The technique where the electron beams are still irreplaceable.

Authors:  Tomasz Piotrowski
Journal:  Rep Pract Oncol Radiother       Date:  2013-12-14

2.  Computer animation body surface analysis of total skin electron radiation therapy dose homogeneity via Cherenkov imaging.

Authors:  Tianshun Miao; Heather Petroccia; Yunhe Xie; Michael Jermyn; Maxine Perroni-Scharf; Namit Kapoor; James M Mahoney; Timothy C Zhu; Petr Bruza; Benjamin B Williams; David J Gladstone; Brian W Pogue
Journal:  J Med Imaging (Bellingham)       Date:  2020-06-03

3.  Light and shadows of a new technique: is photon total-skin irradiation using helical IMRT feasible, less complex and as toxic as the electrons one?

Authors:  Michela Buglione; Luigi Spiazzi; Mauro Urpis; Liliana Baushi; Rossella Avitabile; Nadia Pasinetti; Paolo Borghetti; Luca Triggiani; Sara Pedretti; Federica Saiani; Alfredo Fiume; Diana Greco; Stefano Ciccarelli; Alessia Polonini; Renzo Moretti; Stefano Maria Magrini
Journal:  Radiat Oncol       Date:  2018-08-29       Impact factor: 3.481

4.  Validation of the dosimetry of total skin irradiation techniques by Monte Carlo simulation.

Authors:  Ruiqi Li; Wenchih Tseng; Qiuwen Wu
Journal:  J Appl Clin Med Phys       Date:  2020-06-19       Impact factor: 2.102

5.  In vivo monitoring of total skin electron dose using optically stimulated luminescence dosimeters.

Authors:  Tanya Kairn; Rachael Wilks; Liting Yu; Craig Lancaster; Scott B Crowe
Journal:  Rep Pract Oncol Radiother       Date:  2019-12-16

6.  Electron Scattering in Conventional Cell Flask Experiments and Dose Distribution Dependency.

Authors:  Jeremy S Haskins; Stephen K Martinez; Madison Engstrom; Mami Murakami; Takashi Mori; Del Leary; Takamitsu A Kato
Journal:  Sci Rep       Date:  2020-01-16       Impact factor: 4.379

  6 in total

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