Karlijn J Joling1, Harm W J van Marwijk2, Aaltje E Veldhuijzen2, Henriëtte E van der Horst2, Philip Scheltens3, Filip Smit4, Hein P J van Hout2. 1. Departments of General Practice & Elderly Care Medicine, VU University Medical Centre, EMGO+ Institute for Health and Health Care Research, Amsterdam, The Netherlands. Electronic address: k.joling@vumc.nl. 2. Departments of General Practice & Elderly Care Medicine, VU University Medical Centre, EMGO+ Institute for Health and Health Care Research, Amsterdam, The Netherlands. 3. Department of Neurology, VUmc Alzheimer Center, Amsterdam, The Netherlands. 4. Departments of Clinical Psychology and Epidemiology & Biostatistics, VU University Medical Centre, EMGO+ Institute for Health and Health Care Research, Amsterdam, The Netherlands; Trimbos Institute (Netherlands Institute for Mental Health and Addiction), Utrecht, The Netherlands.
Abstract
OBJECTIVE: Caregivers of persons with dementia play an important and economically valuable role within society, but many may do so at a considerable cost to themselves. Knowing which caregivers have the highest risk of developing a mental disorder may contribute to better support of ultra-high-risk groups with preventive interventions. This study aims to describe the incidence of depression and anxiety disorders in caregivers and to identify its significant predictors. DESIGN: Prospective cohort study with a follow-up of 24 months. PARTICIPANTS: 181 spousal caregivers of persons with dementia without a clinical depression or anxiety disorder at baseline. SETTING: Memory clinics, case management services, and primary care settings in the Netherlands. MEASUREMENTS: The onset of depression and anxiety was measured every 3 months with the MINI International Neuropsychiatric Interview, a structured diagnostic instrument for DSM-IV mental disorders. Potential predictors were assessed at baseline. RESULTS: 60% of the caregivers developed a depressive and/or anxiety disorder within 24 months: 37% a depression, 55% an anxiety disorder, and 32% both disorders. Sub-threshold depressive symptoms (Wald χ2=6.20, df=1, OR: 3.2, 95% CI: 1.28-8.03, p=0.013) and poor self-reported health of the caregiver (Wald χ2=5.56, df=1, OR: 1.17, 95% CI: 1.03-1.34, p=0.018) at baseline were significant predictors of disorder onset. CONCLUSION: Spousal caregivers of persons with dementia have a high risk to develop a mental disorder. Indicators related to the caregiver's (mental) health rather than environmental stressors such as patient characteristics or interruption of caregivers' daily activities predict disorder onset and can be used to identify caregivers for whom supporting preventive interventions are indicated.
OBJECTIVE: Caregivers of persons with dementia play an important and economically valuable role within society, but many may do so at a considerable cost to themselves. Knowing which caregivers have the highest risk of developing a mental disorder may contribute to better support of ultra-high-risk groups with preventive interventions. This study aims to describe the incidence of depression and anxiety disorders in caregivers and to identify its significant predictors. DESIGN: Prospective cohort study with a follow-up of 24 months. PARTICIPANTS: 181 spousal caregivers of persons with dementia without a clinical depression or anxiety disorder at baseline. SETTING: Memory clinics, case management services, and primary care settings in the Netherlands. MEASUREMENTS: The onset of depression and anxiety was measured every 3 months with the MINI International Neuropsychiatric Interview, a structured diagnostic instrument for DSM-IV mental disorders. Potential predictors were assessed at baseline. RESULTS: 60% of the caregivers developed a depressive and/or anxiety disorder within 24 months: 37% a depression, 55% an anxiety disorder, and 32% both disorders. Sub-threshold depressive symptoms (Wald χ2=6.20, df=1, OR: 3.2, 95% CI: 1.28-8.03, p=0.013) and poor self-reported health of the caregiver (Wald χ2=5.56, df=1, OR: 1.17, 95% CI: 1.03-1.34, p=0.018) at baseline were significant predictors of disorder onset. CONCLUSION: Spousal caregivers of persons with dementia have a high risk to develop a mental disorder. Indicators related to the caregiver's (mental) health rather than environmental stressors such as patient characteristics or interruption of caregivers' daily activities predict disorder onset and can be used to identify caregivers for whom supporting preventive interventions are indicated.
Authors: Kristin L Corey; Mary K McCurry; Kristen A Sethares; Meg Bourbonniere; Karen B Hirschman; Salimah H Meghani Journal: Aging Ment Health Date: 2018-12-27 Impact factor: 3.658
Authors: Stephen F Smagula; Helmet T Karim; Tamer S Ibrahim; Robert T Krafty; Sarah T Stahl; Juleen Rodakowski; Charles F Reynolds; Martica H Hall; Howard J Aizenstein Journal: J Gerontol B Psychol Sci Soc Sci Date: 2021-06-14 Impact factor: 4.077
Authors: Stephen F Smagula; Robert T Krafty; Briana J Taylor; Lynn M Martire; Richard Schulz; Martica H Hall Journal: J Sleep Res Date: 2017-05-10 Impact factor: 3.981
Authors: Noelle E Carlozzi; Carey W Sherman; Kaley Angers; Mitchell P Belanger; Amy M Austin; Kelly A Ryan Journal: Aging Ment Health Date: 2017-07-12 Impact factor: 3.658
Authors: Jan R Oyebode; Simon Pini; Emma Ingleson; Molly Megson; Mike Horton; Linda Clare; Hareth Al-Janabi; Carol Brayne; Penny Wright Journal: Patient Date: 2019-02 Impact factor: 3.883