BACKGROUND: Obstructive sleep apnea (OSA) is frequent in acute stroke patients, and has been associated with higher mortality and worse prognosis. Polysomnography (PSG) is the gold standard diagnostic method for OSA, but it is impracticable as a routine for all acute stroke patients. We evaluated the accuracy of two OSA screening tools, the Berlin Questionnaire (BQ), and the Epworth Sleepiness Scale (ESS) when administered to relatives of acute stroke patients; we also compared these tools against a combined screening score (SOS score). METHODS: Ischemic stroke patients were submitted to a full PSG at the first night after onset of symptoms. OSA severity was measured by apnea-hypopnea index (AHI). BQ and ESS were administered to relatives of stroke patients before the PSG and compared to SOS score for accuracy and C-statistics. RESULTS: We prospectively studied 39 patients. OSA (AHI ≥10/h) was present in 76.9%. The SOS score [area under the curve (AUC): 0.812; P = 0.005] and ESS (AUC: 0.789; P = 0.009) had good predictive value for OSA. The SOS score was the only tool with significant predictive value (AUC: 0.686; P = 0.048) for severe OSA (AHI ≥30/h), when compared to ESS (P = 0.119) and BQ (P = 0.191). The threshold of SOS ≤10 showed high sensitivity (90%) and negative predictive value (96.2%) for OSA; SOS ≥20 showed high specificity (100%) and positive predictive value (92.5%) for severe OSA. CONCLUSIONS: The SOS score administered to relatives of stroke patients is a useful tool to screen for OSA and may decrease the need for PSG in acute stroke setting.
BACKGROUND:Obstructive sleep apnea (OSA) is frequent in acute strokepatients, and has been associated with higher mortality and worse prognosis. Polysomnography (PSG) is the gold standard diagnostic method for OSA, but it is impracticable as a routine for all acute strokepatients. We evaluated the accuracy of two OSA screening tools, the Berlin Questionnaire (BQ), and the Epworth Sleepiness Scale (ESS) when administered to relatives of acute strokepatients; we also compared these tools against a combined screening score (SOS score). METHODS: Ischemic strokepatients were submitted to a full PSG at the first night after onset of symptoms. OSA severity was measured by apnea-hypopnea index (AHI). BQ and ESS were administered to relatives of strokepatients before the PSG and compared to SOS score for accuracy and C-statistics. RESULTS: We prospectively studied 39 patients. OSA (AHI ≥10/h) was present in 76.9%. The SOS score [area under the curve (AUC): 0.812; P = 0.005] and ESS (AUC: 0.789; P = 0.009) had good predictive value for OSA. The SOS score was the only tool with significant predictive value (AUC: 0.686; P = 0.048) for severe OSA (AHI ≥30/h), when compared to ESS (P = 0.119) and BQ (P = 0.191). The threshold of SOS ≤10 showed high sensitivity (90%) and negative predictive value (96.2%) for OSA; SOS ≥20 showed high specificity (100%) and positive predictive value (92.5%) for severe OSA. CONCLUSIONS: The SOS score administered to relatives of strokepatients is a useful tool to screen for OSA and may decrease the need for PSG in acute stroke setting.
Authors: Devin L Brown; Kevin He; Sehee Kim; Chia-Wei Hsu; Erin Case; Ronald D Chervin; Lynda D Lisabeth Journal: Sleep Med Date: 2020-05-15 Impact factor: 3.492
Authors: Renan C Castello-Branco; Thiago Cerqueira-Silva; Alisson L Andrade; Beatriz M M Gonçalves; Camila B Pereira; Iuri F Felix; Leila S B Santos; Louise M Porto; Maria E L Marques; Marilia B Catto; Murilo A Oliveira; Paulo R S P de Sousa; Pedro J R Muiños; Renata M Maia; Saul Schnitman; Jamary Oliveira-Filho Journal: J Am Heart Assoc Date: 2020-03-13 Impact factor: 5.501
Authors: Sebastian R Ott; Francesco Fanfulla; Silvia Miano; Thomas Horvath; Andrea Seiler; Corrado Bernasconi; Carlo W Cereda; Anne-Kathrin Brill; Peter Young; Lino Nobili; Mauro Manconi; Claudio L A Bassetti Journal: ERJ Open Res Date: 2020-06-15
Authors: Agustin Leandro Folgueira; Stella Maris Valiensi; Laura De Francesco; Elda Cecilia Berrozpe; Julieta Quiroga Narvaez; Oscar Adolfo Martínez; Pablo Bonardo Journal: Rev Fac Cien Med Univ Nac Cordoba Date: 2021-08-24