| Literature DB >> 24932825 |
Sonja Katayama1, Markus Hantschke, Steffen Lissner, Katja Lindel, Dieter Oetzel, Klaus Herfarth, Juergen Debus, Florian Sterzing.
Abstract
Scalp angiosarcoma represents a therapeutic challenge to all disciplines. This case report demonstrates the potential usefulness of helical tomotherapy (HT) as a new radiotherapeutic treatment option. A 71-year-old woman presented with a superficial angiosarcoma of the scalp, forehead, and left pre- and postauricular areas, with several nodular ulcerating and bleeding lesions. Irradiation of the gross tumor was performed with a total dose of 70 Gy in 2-Gy fractions and of the left cervical lymph nodes with 56 Gy in 1.6-Gy fractions. Good target coverage was achieved without compromising organs at risk, notably the brain. Treatment was very fast (661 seconds per fraction) and was administered with minimal acute toxicity (National Cancer Institute Common Toxicity Criteria: grade 2 erythema and grade 2 dysphagia). During treatment, tumor nodules dissolved into hyperkeratosis. We conclude that with HT, irradiation of the scalp and cervical lymph nodes can be conducted with minimal acute toxicity and without junction problems.Entities:
Mesh:
Year: 2014 PMID: 24932825
Source DB: PubMed Journal: Ear Nose Throat J ISSN: 0145-5613 Impact factor: 1.697