Literature DB >> 24930981

The effects of moderate alcohol concentrations on driving and cognitive performance during ascending and descending blood alcohol concentrations.

Nicola J Starkey1, Samuel G Charlton.   

Abstract

OBJECTIVE: Alcohol has an adverse effect on driving performance; however, the effects of moderate doses on different aspects of the driving task are inconsistent and differ across the intoxication curve. This research aimed to investigate driving and cognitive performance asymmetries (acute tolerance and acute protracted error) accompanying the onset and recovery from moderate alcohol consumption.
METHODS: Sixty-one participants received a placebo, medium (target blood alcohol concentration [BAC] 0.05 mg/ml) or high (target BAC 0.08 mg/ml) dose of alcohol. Participants completed a simulated drive, cognitive tests and subjective rating scales five times over a 3.5 h period.
RESULTS: When ascending and descending BACs (0.05 and 0.09 mg/ml) were compared participants' self-ratings of intoxication and willingness to drive showed acute tolerance. Acute protracted errors were observed for response speed, maze learning errors, time exceeding the speed limit and exaggerated steering responses to hazards.
CONCLUSIONS: Participants' estimates of their level of intoxication were poorly related to their actual BAC levels (and hence degree of impairment), and various aspects of driving and cognitive performance worsened during descending BACs. This indicates that drivers are not good at judging their fitness to drive after drinking only moderate amounts of alcohol and suggests an important focus for public education regarding alcohol and driving.
Copyright © 2014 John Wiley & Sons, Ltd.

Entities:  

Keywords:  acute protracted error; acute tolerance; alcohol; cognitive performance; driving; subjective intoxication

Mesh:

Substances:

Year:  2014        PMID: 24930981     DOI: 10.1002/hup.2415

Source DB:  PubMed          Journal:  Hum Psychopharmacol        ISSN: 0885-6222            Impact factor:   1.672


  5 in total

1.  Effect of chronic opioid therapy on actual driving performance in non-cancer pain patients.

Authors:  Markus B Schumacher; Stefan Jongen; Anja Knoche; Frank Petzke; Eric F Vuurman; Mark Vollrath; Johannes G Ramaekers
Journal:  Psychopharmacology (Berl)       Date:  2017-02-12       Impact factor: 4.530

2.  Effects of methadone plus alcohol on cognitive performance in methadone-maintained volunteers.

Authors:  Bethea A Kleykamp; Ryan G Vandrey; George E Bigelow; Eric C Strain; Miriam Z Mintzer
Journal:  Am J Drug Alcohol Abuse       Date:  2015-01-13       Impact factor: 3.829

3.  Can an app help identify psychomotor function impairments during drinking occasions in the real world? A mixed-method pilot study.

Authors:  Brian Suffoletto; Akash Goyal; Juan Carlos Puyana; Tammy Chung
Journal:  Subst Abus       Date:  2017 Oct-Dec       Impact factor: 3.716

Review 4.  Biomolecules and Biomarkers Used in Diagnosis of Alcohol Drinking and in Monitoring Therapeutic Interventions.

Authors:  Radu M Nanau; Manuela G Neuman
Journal:  Biomolecules       Date:  2015-06-29

Review 5.  Alcohol consumption for simulated driving performance: A systematic review.

Authors:  Mohammad Saeid Rezaee-Zavareh; Payman Salamati; Mahdi Ramezani-Binabaj; Mina Saeidnejad; Mansoureh Rousta; Farhad Shokraneh; Vafa Rahimi-Movaghar
Journal:  Chin J Traumatol       Date:  2017-04-14
  5 in total

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