Literature DB >> 24927929

ESHRE task force on ethics and Law22: preimplantation genetic diagnosis.

G De Wert1, W Dondorp2, F Shenfield3, P Devroey4, B Tarlatzis5, P Barri6, K Diedrich7, V Provoost8, G Pennings8.   

Abstract

This Task Force document discusses some relatively unexplored ethical issues involved in preimplantation genetic diagnosis (PGD). The document starts from the wide consensus that PGD is ethically acceptable if aimed at helping at-risk couples to avoid having a child with a serious disorder. However, if understood as a limit to acceptable indications for PGD, this 'medical model' may turn out too restrictive. The document discusses a range of possible requests for PGD that for different reasons fall outwith the accepted model and argues that instead of rejecting those requests out of hand, they need to be independently assessed in the light of ethical criteria. Whereas, for instance, there is no good reason for rejecting PGD in order to avoid health problems in a third generation (where the second generation would be healthy but faced with burdensome reproductive choices if wanting to have children), using PGD to make sure that one's child will have the same disorder or handicap as its parents, is ethically unacceptable.
© The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  PGD; ethics; indications; transfer decisions

Mesh:

Year:  2014        PMID: 24927929     DOI: 10.1093/humrep/deu132

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  16 in total

Review 1.  Preimplantation genetic diagnosis: an update on current technologies and ethical considerations.

Authors:  Kou Sueoka
Journal:  Reprod Med Biol       Date:  2015-11-14

2.  Public Perceptions of Ethical, Legal and Social Implications of Pre-implantation Genetic Diagnosis (PGD) in Malaysia.

Authors:  Angelina P Olesen; Siti Nurani Mohd Nor; Latifah Amin; Anisah Che Ngah
Journal:  Sci Eng Ethics       Date:  2016-12-19       Impact factor: 3.525

Review 3.  A systematic review of the views of healthcare professionals on the scope of preimplantation genetic testing.

Authors:  Maria Siermann; Zoë Claesen; Laurent Pasquier; Taneli Raivio; Olga Tšuiko; Joris Robert Vermeesch; Pascal Borry
Journal:  J Community Genet       Date:  2022-01-14

4.  Acceptable applications of preimplantation genetic diagnosis (PGD) among Israeli PGD users.

Authors:  Shachar Zuckerman; David A Zeevi; Sigal Gooldin; Gheona Altarescu
Journal:  Eur J Hum Genet       Date:  2017-07-26       Impact factor: 4.246

5.  New Promising Strategies in Oncofertility.

Authors:  Janella N Hudson; Nathanael B Stanley; Leena Nahata; Meghan Bowman-Curci; Gwendolyn P Quinn
Journal:  Expert Rev Qual Life Cancer Care       Date:  2017-03-28

6.  What Israeli policy can teach us about elective sex selection.

Authors:  Gila Leiter
Journal:  Isr J Health Policy Res       Date:  2014-12-18

7.  Transferring embryos with indeterminate PGD results: the ethical implications.

Authors:  Iris G Insogna; Elizabeth Ginsburg
Journal:  Fertil Res Pract       Date:  2016-02-01

Review 8.  Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.

Authors:  Rick Kamps; Rita D Brandão; Bianca J van den Bosch; Aimee D C Paulussen; Sofia Xanthoulea; Marinus J Blok; Andrea Romano
Journal:  Int J Mol Sci       Date:  2017-01-31       Impact factor: 5.923

9.  Dealing with treatment and transfer requests: how PGD-professionals discuss ethical challenges arising in everyday practice.

Authors:  Melisa Soto-Lafontaine; Wybo Dondorp; Veerle Provoost; Guido de Wert
Journal:  Med Health Care Philos       Date:  2018-09

Review 10.  FMR1 CGG repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile X syndrome.

Authors:  Indhu-Shree Rajan-Babu; Mulias Lian; Felicia S H Cheah; Min Chen; Arnold S C Tan; Ethiraj B Prasath; Seong Feei Loh; Samuel S Chong
Journal:  Expert Rev Mol Med       Date:  2017-07-19       Impact factor: 5.600

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