Literature DB >> 24925833

Anatomic complexity quantitated by nephrometry score is associated with prolonged warm ischemia time during robotic partial nephrectomy.

Jeffrey J Tomaszewski1, Marc C Smaldone2, Reza Mehrazin2, Neil Kocher2, Timothy Ito2, Philip Abbosh2, Jacob Baber2, Alexander Kutikov2, Rosalia Viterbo2, David Y T Chen2, Daniel J Canter2, Robert G Uzzo2.   

Abstract

OBJECTIVE: To assess the association between nephrometry score (NS) and prolonged warm ischemia time (WIT) in patients undergoing robotic partial nephrectomy (RPN) for clinically localized renal masses.
METHODS: We queried our prospectively maintained kidney cancer database to identify all patients undergoing RPN for localized tumors from 2007-2012. Patient and tumor characteristics were compared between complexity groups using analysis of variance and chi square tests. Multivariate logistic regression models were used to examine the relationship between NS complexity and warm ischemia >30 minutes.
RESULTS: Three hundred seventy-five patients (mean age, 59 ± 11 years; mean Charlson comorbidity index, 1.0 ± 1.3) undergoing RPN under warm ischemia for clinically localized renal tumors (mean tumor size, 3.1 ± 1.5 cm; mean NS, 6.8 ± 1.8) met inclusion criteria and had NS available. Stratified by complexity, groups differed with respect to age at surgery, tumor size, proximity to the hilum, collecting system entry, estimated blood loss, and operative time (all P values ≤.05). Significant differences in mean WIT were observed when comparing low (19.4 ± 12.1 minutes), intermediate (28.6 ± 12.8 minutes), and high (36.1 ± 13.7 minutes) NS complexity groups (P <.0001). Adjusting for confounders, patients with intermediate (odds ratio, 2.1; confidence interval, 1.2-3.9) and high (odds ratio, 3.7; confidence interval, 1.1-11.8) NS complexity were more likely to require prolonged WIT when compared with patients with low complexity tumors.
CONCLUSION: In our large institutional cohort, quantification of anatomic complexity using the NS is associated with WIT >30 minutes in patients undergoing RPN for localized renal tumors. This provides further evidence that standardized reporting of tumor anatomic complexity affords meaningful outcome comparisons.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24925833      PMCID: PMC4114993          DOI: 10.1016/j.urology.2014.04.013

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  30 in total

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4.  Does nephrometry scoring of renal tumors predict outcomes in patients selected for robot-assisted partial nephrectomy?

Authors:  Patrick W Mufarrij; L Spencer Krane; Srinivas Rajamahanty; Ashok K Hemal
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5.  Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function.

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6.  Outcomes of robotic partial nephrectomy for renal masses with nephrometry score of ≥7.

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8.  The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth.

Authors:  Alexander Kutikov; Robert G Uzzo
Journal:  J Urol       Date:  2009-07-17       Impact factor: 7.450

9.  Robotic partial nephrectomy for complex renal tumors: surgical technique.

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Review 10.  Assessing the impact of ischaemia time during partial nephrectomy.

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3.  Tumor diameter accurately predicts perioperative outcomes in T1 renal cancer treated with robot-assisted partial nephrectomy.

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Review 5.  Robot-assisted partial nephrectomy for moderate to highly complex renal masses. A systematic review and meta-analysis.

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6.  Development and In Vitro Assessment of a Novel Vacuum-Based Tissue-Holding Device for Laparoscopic and Robotic Kidney Cancer Operations.

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