Giuseppe Lippi1, Fernanda Pavesi2, Mirco Bardi2, Silvia Pipitone2. 1. Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Italy. Electronic address: glippi@ao.pr.it. 2. Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Italy.
Abstract
OBJECTIVES: To assess analytical imprecision and comparability of red blood cell distribution width (RDW) on Abbott Sapphire, Mindray BC6800, Siemens Advia 2120 and Sysmex XE-5000. DESIGN AND METHODS: Within-run imprecision was assessed on three pools and comparability using 132 inpatient samples. RESULTS: The imprecision of RDW was comprised between 0.3 and 1.2%, but the values exhibited broad variation among different analyzers, with bias exceeding the desirable quality specifications. CONCLUSIONS: Harmonization of RDW is still an unmet need.
OBJECTIVES: To assess analytical imprecision and comparability of red blood cell distribution width (RDW) on Abbott Sapphire, Mindray BC6800, Siemens Advia 2120 and Sysmex XE-5000. DESIGN AND METHODS: Within-run imprecision was assessed on three pools and comparability using 132 inpatient samples. RESULTS: The imprecision of RDW was comprised between 0.3 and 1.2%, but the values exhibited broad variation among different analyzers, with bias exceeding the desirable quality specifications. CONCLUSIONS: Harmonization of RDW is still an unmet need.
Authors: Gabriela de Jonge; Talita L Dos Santos; Bruno R Cruz; Mackelly Simionatto; Jeanine I M Bittencourt; Everson A Krum; Mariane F Moss; Danielle Cristyane K Borato Journal: J Clin Lab Anal Date: 2018-02-03 Impact factor: 2.352
Authors: Carlos Martinez; Carmel T Mooney; Robert E Shiel; Pak Kan Tang; Louise Mooney; Emma J O'Neill Journal: Can Vet J Date: 2019-09 Impact factor: 1.008