Literature DB >> 24924699

Emergency surgery for perforated diverticulitis in the immunosuppressed patient.

T Golda1, E Kreisler, C Mercader, R Frago, L Trenti, S Biondo.   

Abstract

AIM: Immunosuppression is believed to worsen outcomes for patients who require surgery for perforated diverticulitis. The aim of this study was to compare surgical outcomes between immunocompromised and immunocompetent patients undergoing surgery for complicated diverticulitis.
METHOD: All patients who underwent emergency surgery for complicated diverticulitis between 2004 and 2012 in a single unit were studied. Patients were classified as immunosuppressed (group I) or immunocompetent (group II). Operation type and postoperative morbidity and mortality were compared between groups. The impact of operating surgeons' specialization and the Peritonitis Severity Score (PSS) were also evaluated to determine their impact on the restoration of gastrointestinal (GI) continuity.
RESULTS: One-hundred and sixteen patients (mean age: 63.7 years), 41.4% women, were included. Fifty-three (45.7%) patients were immunosuppressed (group I): 42 underwent Hartmann's procedure (HP) (79.2%), nine (17.0%) underwent resection and primary anastomosis (RPA) with ileostomy (IL) and two (3.8%) underwent RPA without IL. In group II, 15 HP (23.8%), nine RPA with IL (14.3%) and 39 RPA without IL (61.9%) were performed. Postoperative morbidity and mortality were 79.2% and 26.4%, respectively, in group I and 63.5% and 6.3%, respectively, in group II. The overall mean PSS was 9.5, with a mean PSS of 11.1 in group I and of 8.1 in group II. The decision to perform a primary anastomosis differed significantly between colorectal surgeons and general surgeons in the patients with a PSS of 9-10-11.
CONCLUSION: In immunocompromised patients, RPA with IL can be a safe surgical option, whereas HP should be reserved for patients with a PSS of > 11. Colorectal surgical specialization is associated with higher rates of restoration of GI continuity in patients with perforated diverticulitis, especially in patients with an intermediate PSS score. Evaluation of each patient's PSS facilitates decision making in surgery for perforated diverticulitis. Colorectal Disease
© 2014 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  Diverticulitis; Peritonitis Severity Score; immunosuppression; left colonic perforation

Mesh:

Substances:

Year:  2014        PMID: 24924699     DOI: 10.1111/codi.12685

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  7 in total

1.  The Effect of Immunosuppression on Emergency Colectomy Outcomes: A Nationwide Retrospective Analysis.

Authors:  Majed W El Hechi; Jae Moo Lee; Leon Naar; Mohamad El Moheb; Nikolaos Kokoroskos; George C Velmahos; Noelle N Saillant; Haytham M A Kaafarani; April E Mendoza
Journal:  World J Surg       Date:  2020-05       Impact factor: 3.352

2.  Incidence and Risk Factors of Abdominal Complications After Lung Transplantation.

Authors:  Fabian Grass; Markus Schäfer; Alessandra Cristaudi; Carine Berutto; John-David Aubert; Michel Gonzalez; Nicolas Demartines; Hans-Beat Ris; Paola M Soccal; Thorsten Krueger
Journal:  World J Surg       Date:  2015-09       Impact factor: 3.352

3.  Colectomy with ileostomy for severe ulcerative colitis-postoperative complications and risk factors.

Authors:  C Schineis; K S Lehmann; J C Lauscher; K Beyer; L Hartmann; G A Margonis; J Michel; C E Degro; F N Loch; F Speichinger; M E Kreis; C Kamphues
Journal:  Int J Colorectal Dis       Date:  2019-12-21       Impact factor: 2.571

Review 4.  Special Situations in the Management of Diverticular Disease.

Authors:  Elizabeth H Wood; Michael M Sigman; Dana M Hayden
Journal:  Clin Colon Rectal Surg       Date:  2021-02-24

5.  Surgical management in immunosuppressed patients with sigmoid diverticulitis, still a challenge: a single-center observational study.

Authors:  Sascha Vaghiri; Dimitrios Prassas; Wolfram Trudo Knoefel; Andreas Krieg
Journal:  Int J Colorectal Dis       Date:  2022-08-02       Impact factor: 2.796

6.  Elective Surgery for Diverticulitis and the Risk of Recurrence and Ostomy.

Authors:  Lucas W Thornblade; Vlad V Simianu; Giana H Davidson; David R Flum
Journal:  Ann Surg       Date:  2021-06-01       Impact factor: 13.787

Review 7.  Management of perforated diverticulitis with generalized peritonitis. A multidisciplinary review and position paper.

Authors:  R Nascimbeni; A Amato; R Cirocchi; A Serventi; A Laghi; M Bellini; G Tellan; M Zago; C Scarpignato; G A Binda
Journal:  Tech Coloproctol       Date:  2020-11-05       Impact factor: 3.781

  7 in total

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