Literature DB >> 24924580

Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry.

Jakob Ledwoch1, Jennifer Franke, Stephan Baldus, Wolfgang Schillinger, Raffi Bekeredjian, Peter Boekstegers, Ulrich Hink, Karl-Heinz Kuck, Taoufik Ouarrak, Helge Möllmann, Georg Nickenig, Jochen Senges, Olaf Franzen, Horst Sievert.   

Abstract

AIMS: This analysis from the German Mitral Valve Registry investigates the impact of the learning curve with the MitraClip(®) technique on procedural success and complications. METHODS AND
RESULTS: Consecutive patients treated since 2009 in centers that performed more than 50 transcatheter mitral repairs were included. Results of the first half of the patients were compared to those of the second. Altogether 496 patients from 10 centers were included. Patients treated later had less common severe heart failure symptoms (patients with NYHA IV: 22.1 vs. 14.5 %, p < 0.05). The EuroSCORE I (22.0 vs. 23.0 %, p = ns) and Society of Thoracic Surgeons (STS) score (7.5 vs. 9.5 %, p = ns) did not differ between both groups. Procedural success was 95.6 % (238/249) in the first cases and 94.7 % (232/245, p = ns) subsequently. Also procedural time (104.3 vs. 119 min, p = ns) and complications did not decrease over time.
CONCLUSION: A learning curve using the MitraClip(®) device does not appear to significantly affect acute MR reduction, hospital and 30-day mortality. Most likely, the proctor system leads to already high initial procedure success and relatively short procedure time.

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Year:  2014        PMID: 24924580     DOI: 10.1007/s00392-014-0734-y

Source DB:  PubMed          Journal:  Clin Res Cardiol        ISSN: 1861-0684            Impact factor:   5.460


  23 in total

1.  Risk factors for early mortality after valve surgery in Europe in the 1990s: lessons from the EuroSCORE pilot program.

Authors:  F Roques; S A Nashef; P Michel
Journal:  J Heart Valve Dis       Date:  2001-09

Review 2.  Percutaneous interventional mitral regurgitation treatment using the Mitra-Clip system.

Authors:  P Boekstegers; J Hausleiter; S Baldus; R S von Bardeleben; H Beucher; C Butter; O Franzen; R Hoffmann; H Ince; K H Kuck; V Rudolph; U Schäfer; W Schillinger; N Wunderlich
Journal:  Clin Res Cardiol       Date:  2014-02       Impact factor: 5.460

3.  Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST Phase I Clinical Trial.

Authors:  Ted Feldman; Hal S Wasserman; Howard C Herrmann; William Gray; Peter C Block; Patrick Whitlow; Fred St Goar; Leonardo Rodriguez; Frank Silvestry; Allan Schwartz; Timothy A Sanborn; Jose A Condado; Elyse Foster
Journal:  J Am Coll Cardiol       Date:  2005-10-19       Impact factor: 24.094

4.  One- and twelve-month safety and efficacy outcomes of patients undergoing edge-to-edge percutaneous mitral valve repair (from the GRASP Registry).

Authors:  Carmelo Grasso; Davide Capodanno; Salvatore Scandura; Stefano Cannata; Sebastiano Immè; Sarah Mangiafico; Anna Pistritto; Margherita Ministeri; Marco Barbanti; Anna Caggegi; Marta Chiarandà; Fabio Dipasqua; Sandra Giaquinta; Michele Occhipinti; Gianpaolo Ussia; Corrado Tamburino
Journal:  Am J Cardiol       Date:  2013-02-20       Impact factor: 2.778

5.  Promising results after percutaneous mitral valve repair.

Authors:  Nikolaj Ihlemann; Olaf Franzen; Erik Jørgensen; Peter Bo Hansen; Christian Hassager; Jacob Eifer Møller; Lars Søndergaard
Journal:  Dan Med Bull       Date:  2011-07

6.  Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction.

Authors:  Olaf Franzen; Stephan Baldus; Volker Rudolph; Sven Meyer; Malgorzata Knap; Dietmar Koschyk; Hendrik Treede; Achim Barmeyer; Joachim Schofer; Angelika Costard-Jäckle; Michael Schlüter; Hermann Reichenspurner; Thomas Meinertz
Journal:  Eur Heart J       Date:  2010-03-10       Impact factor: 29.983

7.  Percutaneous mitral valve repair using the edge-to-edge technique in a high-risk population.

Authors:  B J L Van den Branden; M C Post; M J Swaans; B J W M Rensing; F D Eefting; H W M Plokker; W Jaarsma; J A S Van der Heyden
Journal:  Neth Heart J       Date:  2010-09       Impact factor: 2.380

8.  MitraClip therapy in daily clinical practice: initial results from the German transcatheter mitral valve interventions (TRAMI) registry.

Authors:  Stephan Baldus; Wolfgang Schillinger; Olaf Franzen; Raffi Bekeredjian; Horst Sievert; Joachim Schofer; Karl-Heinz Kuck; Thomas Konorza; Helge Möllmann; Christoph Hehrlein; Taoufik Ouarrak; Jochen Senges; Thomas Meinertz
Journal:  Eur J Heart Fail       Date:  2012-06-08       Impact factor: 15.534

9.  Impact of the learning curve on outcomes after percutaneous mitral valve repair with MitraClip and lessons learned after the first 75 consecutive patients.

Authors:  Wolfgang Schillinger; Thomas Athanasiou; Ninja Weicken; Lars Berg; Tobias Tichelbäcker; Miriam Puls; Mark Hünlich; Rolf Wachter; Hans-Joachim Helms; Ralf Seipelt; Friedrich A Schöndube; Gerd Hasenfuss
Journal:  Eur J Heart Fail       Date:  2011-10-24       Impact factor: 15.534

10.  Acute safety and 30-day outcome after percutaneous edge-to-edge repair of mitral regurgitation in very high-risk patients.

Authors:  Sven T Pleger; Derliz Mereles; Marius Schulz-Schönhagen; Ulrike Krumsdorf; Emmanuel Chorianopoulos; Wolfgang Rottbauer; Hugo A Katus; Raffi Bekeredjian
Journal:  Am J Cardiol       Date:  2011-09-03       Impact factor: 2.778

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  6 in total

Review 1.  Cardiac surgery 2014 reviewed.

Authors:  Torsten Doenst; Constanze Strüning; Alexandros Moschovas; David Gonzalez-Lopez; Ilija Valchanov; Hristo Kirov; Mahmoud Diab; Gloria Faerber
Journal:  Clin Res Cardiol       Date:  2015-09-24       Impact factor: 5.460

2.  Deep sedation versus general anesthesia in percutaneous edge-to-edge mitral valve reconstruction using the MitraClip system.

Authors:  Suzanne de Waha; Joerg Seeburger; Joerg Ender; Steffen Desch; Ingo Eitel; Adrian Reinhardt; Janine Pöss; Georg Fuernau; Thilo Noack; Denis Rouven Merk; Gerhard Schuler; Hans-Hinrich Sievers; Friedrich-Wilhelm Mohr; Holger Thiele
Journal:  Clin Res Cardiol       Date:  2015-12-18       Impact factor: 5.460

Review 3.  Mitral Regurgitation - A Multidisciplinary Challenge.

Authors:  Eduardo Alegria-Barrero; Olaf W Franzen
Journal:  Eur Cardiol       Date:  2014-07

4.  Large-scale experience with an anchorless vascular closure device in a real-life clinical setting.

Authors:  Verena Schelp; Sandra Freitag-Wolf; Dieter Hinzmann; Peter Bramlage; Norbert Frey; Derk Frank
Journal:  Clin Res Cardiol       Date:  2014-10-08       Impact factor: 5.460

5.  Impact of cardiac comorbidities on early and 1-year outcome after percutaneous mitral valve interventions: data from the German transcatheter mitral valve interventions (TRAMI) registry.

Authors:  Carsten Schwencke; Klaudija Bijuklic; Taoufik Ouarrak; Edith Lubos; Wolfgang Schillinger; Björn Plicht; Holger Eggebrecht; Stephan Baldus; Gerhard Schymik; Peter Boekstegers; Rainer Hoffmann; Jochen Senges; Joachim Schofer
Journal:  Clin Res Cardiol       Date:  2016-10-17       Impact factor: 5.460

6.  One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry.

Authors:  Miriam Puls; Edith Lubos; Peter Boekstegers; Ralph Stephan von Bardeleben; Taoufik Ouarrak; Christian Butter; Christine S Zuern; Raffi Bekeredjian; Horst Sievert; Georg Nickenig; Holger Eggebrecht; Jochen Senges; Wolfgang Schillinger
Journal:  Eur Heart J       Date:  2015-11-27       Impact factor: 29.983

  6 in total

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