Literature DB >> 24923415

Regulation of crp gene expression by the catabolite repressor/activator, Cra, in Escherichia coli.

Zhongge Zhang1, Mohammad Aboulwafa, Milton H Saier.   

Abstract

Growth of E. coli on several carbon sources is dependent on the catabolite repressor/activator (Cra) protein although a Cra consensus DNA-binding site is not present in the control regions of the relevant catabolic operons. We show that Cra regulates growth by activating expression of the crp gene. It thereby mediates catabolite repression of catabolic operons by an indirect mechanism.
© 2014 S. Karger AG, Basel.

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Year:  2014        PMID: 24923415      PMCID: PMC4125524          DOI: 10.1159/000362722

Source DB:  PubMed          Journal:  J Mol Microbiol Biotechnol        ISSN: 1464-1801


  26 in total

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Review 3.  Transcription activation by catabolite activator protein (CAP).

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8.  Omics analysis coupled with gene editing revealed potential transporters and regulators related to levoglucosan metabolism efficiency of the engineered Escherichia coli.

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9.  Alleviation of carbon catabolite repression in Enterobacter aerogenes for efficient utilization of sugarcane molasses for 2,3-butanediol production.

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