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Literature DB >> 24921040

A Regioselective Synthesis of the Dephospho DIthiolene Protected Molybdopterin.

Igor V Pimkov, Antoinette Peterson, David N Vaccarello, Partha Basu.

Abstract

The molybdopterin (MPT) is a complex molecule, made out of three distinctly different components. A retrosynthetic analysis provides a possible route for its synthesis that utilizes the coupling of a diamine with an osone analog. A regioselective condensation of the diamine with an osone affords the dephospho MPT, which has been characterized by NMR and IR spectroscopies, as well as high-resolution mass spectrometry.

Entities: CellLine Chemical Disease Species

Year: 2014 PMID： 24921040 PMCID： PMC4048723 DOI： 10.1039/C4RA02786H

Source DB: PubMed Journal: RSC Adv ISSN： 2046-2069 Impact factor: 3.361

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