Literature DB >> 24920593

Redemption of autoreactive B cells.

Barton F Haynes1, Laurent Verkoczy2, Garnett Kelsoe3.   

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Year:  2014        PMID： 24920593      PMCID： PMC4078812          DOI： 10.1073/pnas.1407877111

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  32 in total

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2.  Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.

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4.  Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10.

Authors:  Yao Chen; Jinsong Zhang; Kwan-Ki Hwang; Hilary Bouton-Verville; Shi-Mao Xia; Amanda Newman; Ying-Bin Ouyang; Barton F Haynes; Laurent Verkoczy
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7.  Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses.

Authors:  Laurent Verkoczy; Yao Chen; Jinsong Zhang; Hilary Bouton-Verville; Amanda Newman; Bradley Lockwood; Richard M Scearce; David C Montefiori; S Moses Dennison; Shi-Mao Xia; Kwan-Ki Hwang; Hua-Xin Liao; S Munir Alam; Barton F Haynes
Journal:  J Immunol       Date:  2013-08-05       Impact factor: 5.422

8.  B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study.

Authors:  Barton F Haynes; Garnett Kelsoe; Stephen C Harrison; Thomas B Kepler
Journal:  Nat Biotechnol       Date:  2012-05-07       Impact factor: 54.908

9.  A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center.

Authors:  Tanja A Schwickert; Gabriel D Victora; David R Fooksman; Alice O Kamphorst; Monica R Mugnier; Alexander D Gitlin; Michael L Dustin; Michel C Nussenzweig
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10.  Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.

Authors:  Guang Yang; T Matt Holl; Yang Liu; Yi Li; Xiaozhi Lu; Nathan I Nicely; Thomas B Kepler; S Munir Alam; Hua-Xin Liao; Derek W Cain; Leonard Spicer; John L VandeBerg; Barton F Haynes; Garnett Kelsoe
Journal:  J Exp Med       Date:  2013-01-28       Impact factor: 14.307
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1.  Eliminating antibody polyreactivity through addition of N-linked glycosylation.

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Journal:  Protein Sci       Date:  2015-05-12       Impact factor: 6.725

Review 2.  Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.

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Review 3.  Approaches to preventative and therapeutic HIV vaccines.

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Review 4.  Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.

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Journal:  Adv Immunol       Date:  2017       Impact factor: 3.543

5.  The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs.

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Journal:  Blood       Date:  2020-11-12       Impact factor: 22.113

6.  Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.

Authors:  Ruijun Zhang; Laurent Verkoczy; Kevin Wiehe; S Munir Alam; Nathan I Nicely; Sampa Santra; Todd Bradley; Charles W Pemble; Jinsong Zhang; Feng Gao; David C Montefiori; Hilary Bouton-Verville; Garnett Kelsoe; Kevin Larimore; Phillip D Greenberg; Robert Parks; Andrew Foulger; Jessica N Peel; Kan Luo; Xiaozhi Lu; Ashley M Trama; Nathan Vandergrift; Georgia D Tomaras; Thomas B Kepler; M Anthony Moody; Hua-Xin Liao; Barton F Haynes
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7.  High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.

Authors:  Kaval Kaur; Nai-Ying Zheng; Kenneth Smith; Min Huang; Lie Li; Noel T Pauli; Carole J Henry Dunand; Jane-Hwei Lee; Michael Morrissey; Yixuan Wu; Michelle L Joachims; Melissa E Munroe; Denise Lau; Xinyan Qu; Florian Krammer; Jens Wrammert; Peter Palese; Rafi Ahmed; Judith A James; Patrick C Wilson
Journal:  PLoS One       Date:  2015-05-07       Impact factor: 3.240

Review 8.  HIV Vaccination: A Roadmap among Advancements and Concerns.

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  9 in total

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