Literature DB >> 24918693

Evaluation of the effects of recipient/donor gender on early/late postoperative renal graft functions by renal scintigraphy.

Sevin Ayaz1, Esra Arzu Gençoğlu, Gökhan Moray, Mehmet Yavuz Gözükara, Mehmet Haberal.   

Abstract

OBJECTIVES: We discuss the effects of recipient/donor gender on renal allograft functions using scintigraphic parameters obtained 3 days after renal transplant and 1 year after transplant.
MATERIALS AND METHODS: This retrospective study included 76 renal allograft recipients (group one, 38 males; group two, 38 females). Patients underwent scintigraphic imaging with Tc-99m DTPA on postoperative day 3 and 1 year after transplant. We used the Hilson perfusion index, maximum renal activity/background activity, ratio of renal activity at 20 minutes to renal activity at 3 minutes, time-to-peak activity, and glomerular filtration rate to measure quantitative parameters.
RESULTS: On postoperative day 3, the Hilson perfusion index, maximum renal activity/background activity, the ratio of renal activity at 20 minutes to renal activity at 3 minutes, time-to-peak activity, and glomerular filtration rate values for male/female recipients were similar (P = .65, P = .77, P = .38, P = .10, P = .99). The gender of donors was compared with the above-mentioned scintigraphic parameters of the recipients, and no statistically significant differences were found (P = .24, P = .25, P = .44, P = .29, P = .13). At 1-year follow-up, values obtained from group 1 and group 2 recipients were similar. After 1 year, chronic rejection developed in 15.7% of group 1 recipients and in 10.5% of group 2 recipients; acute rejection developed in 21% of group 1 recipients and in 23.6% of group 2 recipients. There were no statistically significant differences between the occurrence of acute rejection and the gender of recipients or donors (P = 1.00, P = .45).
CONCLUSIONS: We observed no statistically significant differences between renal graft functions and gender of the recipients/donors during the early/late posttransplant period.

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Year:  2014        PMID: 24918693     DOI: 10.6002/ect.2013.0275

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  1 in total

Review 1.  Gender Mainstreaming and Transplant Surgery.

Authors:  Eva Maria Teegen; Isabell Krebs; Corinna Langelotz; Johann Pratschke; Beate Rau
Journal:  Visc Med       Date:  2016-07-29
  1 in total

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