Literature DB >> 24914836

Natural history of prostate cancer.

Javier Estebanez1, Antoin Teyrouz, Miguel Angel Gutierrez, Ione Linazasoro, Jon Belloso, Carlos Cano, Jose Maria Peralta, Juan Pablo Sanz.   

Abstract

Prostatic cancer can be a silent tumor, with no symptoms remaining undetectable throughout life . But when it keeps growing, enough to produce symptoms such as bladder neck obstruction, invasion of adjacent organs or distant metastasis, curative treatment is usually impossible. Since PSA emerges, data shows a dramatic increasing in the diagnosis of prostatic cancer, specially low risk tumor. Since then, We are wondering which tumors are suitable to be treated and which ones remain asymptomatic without treatment. Analysing the natural history of prostate cancer, helps us to choose the best atitude treating the tumor, this subjet has been in constant discusión in the last decade. Our article consistes of a reviewing the main publications treating natural history of prostate cancer in prehyphen;and post-PSA era. The indicated studied suggest that most prostate tumors diagnosed today are low grade cancer, as a result with a low mortality. This conclusión shows us the importance of modifying the algorithm of treatment of these tumors.

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Year:  2014        PMID: 24914836

Source DB:  PubMed          Journal:  Arch Esp Urol        ISSN: 0004-0614            Impact factor:   0.436


  4 in total

1.  Complex Systems Biology Approach in Connecting PI3K-Akt and NF-κB Pathways in Prostate Cancer.

Authors:  Eswar Shankar; Michael C Weis; Jayant Avva; Sanjeev Shukla; Meenakshi Shukla; Sree N Sreenath; Sanjay Gupta
Journal:  Cells       Date:  2019-02-26       Impact factor: 6.600

Review 2.  Silent Inflammatory Bowel Disease.

Authors:  Matthew D Coates; David G Binion
Journal:  Crohns Colitis 360       Date:  2021-09-22

3.  Curcumol Inhibits the Development of Prostate Cancer by miR-125a/STAT3 Axis.

Authors:  Wen Sheng; Jin Ding; Lumei Liu; Neng Wang; Baowei Lu; Xujun You; Qinghu He; Qing Zhou
Journal:  Evid Based Complement Alternat Med       Date:  2022-07-30       Impact factor: 2.650

4.  LncRNA SNHG3 sponges miR-577 to up-regulate SMURF1 expression in prostate cancer.

Authors:  Teng Li; Yi Xing; Fan Yang; Yangyang Sun; Shaojin Zhang; Qingwei Wang; Weixing Zhang
Journal:  Cancer Med       Date:  2020-04-05       Impact factor: 4.452

  4 in total

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