Literature DB >> 24913971

Cytotoxicity of compounds from the fruits of Derris indica against cholangiocarcinoma and HepG2 cell lines.

Phatharapoll Decharchoochart1, Jittra Suthiwong, Papavee Samatiwat, Veerapol Kukongviriyapan, Chavi Yenjai.   

Abstract

Two new compounds, derrivanone (1) and derrischalcone (2), were isolated from the crude hexane extract of the fruits of Derris indica. In addition, 14 known compounds were isolated from the fruits of this plant. Chalcones 2-4 showed strong cytotoxicity against cholangiocarcinoma cell line (M156) and human hepatoma HepG2 cells. In addition, flavanones 15 and 16 exhibited potent and high cytotoxic efficacy.

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Year:  2014        PMID： 24913971     DOI： 10.1007/s11418-014-0851-y

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  10 in total

1.  Pongamone A-E, five flavonoids from the stems of a mangrove plant, Pongamia pinnata.

Authors:  Liya Li; Xiang Li; Cui Shi; Zhiwei Deng; Hongzheng Fu; Peter Proksch; Wenhan Lin
Journal:  Phytochemistry       Date:  2006-06-30       Impact factor: 4.072

2.  Antimycobacterial flavonoids from Derris indica.

Authors:  Sorwaporn Koysomboon; Ian van Altena; Shigeru Kato; Kan Chantrapromma
Journal:  Phytochemistry       Date:  2006-05       Impact factor: 4.072

3.  C-prenylflavonoids from roots of Tephrosia tunicata.

Authors:  C C Andrei; D T Ferreira; M Faccione; L A de Moraes; M G de Carvalho; R Braz-Filho
Journal:  Phytochemistry       Date:  2000-12       Impact factor: 4.072

4.  Distinct chemotypes of Tephrosia vogelii and implications for their use in pest control and soil enrichment.

Authors:  Philip C Stevenson; Geoffrey C Kite; Gwilym P Lewis; Félix Forest; Stephen P Nyirenda; Steven R Belmain; Gudeta W Sileshi; Nigel C Veitch
Journal:  Phytochemistry       Date:  2012-04-04       Impact factor: 4.072

5.  Identification of pongamol and karanjin as lead compounds with antihyperglycemic activity from Pongamia pinnata fruits.

Authors:  Akhilesh K Tamrakar; Prem P Yadav; Priti Tiwari; Rakesh Maurya; Arvind K Srivastava
Journal:  J Ethnopharmacol       Date:  2008-05-15       Impact factor: 4.360

6.  The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity.

Authors:  Peter Houghton; Rui Fang; Isariya Techatanawat; Glyn Steventon; Peter J Hylands; C C Lee
Journal:  Methods       Date:  2007-08       Impact factor: 3.608

7.  Furanoflavonoids from Pongamia pinnata fruits.

Authors:  Prem P Yadav; Ghufran Ahmad; Rakesh Maurya
Journal:  Phytochemistry       Date:  2004-02       Impact factor: 4.072

8.  Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis.

Authors:  Cecília T T Blatt; Daniel Chávez; Heebyung Chai; James G Graham; Fernando Cabieses; Norman R Farnsworth; Geoffrey A Cordell; John M Pezzuto; A Douglas Kinghorn
Journal:  Phytother Res       Date:  2002-06       Impact factor: 5.878

9.  Phenethyl isothiocyanate induces apoptosis of cholangiocarcinoma cells through interruption of glutathione and mitochondrial pathway.

Authors:  Ornanong Tusskorn; Auemduan Prawan; Laddawan Senggunprai; Upa Kukongviriyapan; Veerapol Kukongviriyapan
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-08-15       Impact factor: 3.000

10.  Unequivocal assignments of flavonoids from Tephrosia sp. (Fabaceae).

Authors:  A M C Arriaga; J Q Lima; J N Vasconcelos; M C F de Oliveira; M Andrade-Neto; G M P Santiago; D E A Uchoa; G T Malcher; J Mafezoli; R Braz-Filho
Journal:  Magn Reson Chem       Date:  2009-06       Impact factor: 2.447
  10 in total
  4 in total

1.  Antimicrobial, antibiofilm, antioxidant, anticancer, and phytochemical composition of the seed extract of Pongamia pinnata.

Authors:  Minakshi Rajput; Navneet Bithel; Sekar Vijayakumar
Journal:  Arch Microbiol       Date:  2021-05-26       Impact factor: 2.552

2.  Derrisisoflavones H-K and One Isoflavan Derivative from Derris robusta.

Authors:  Guo-Zhu Wei; Mei-Fen Mao; Xiang-Mei Li; Fu-Cai Ren; Fei Wang
Journal:  Nat Prod Bioprospect       Date:  2016-02-19

Review 3.  Research and Development of Atractylodes lancea (Thunb) DC. as a Promising Candidate for Cholangiocarcinoma Chemotherapeutics.

Authors:  Kesara Na-Bangchang; Tullayakorn Plengsuriyakarn; Juntra Karbwang
Journal:  Evid Based Complement Alternat Med       Date:  2017-11-14       Impact factor: 2.629

4.  Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity.

Authors:  Letizia Porcelli; Rosa Maria Iacobazzi; Anna Elisa Quatrale; Carlo Bergamini; Nunzio Denora; Pasquale Crupi; Donato Antonacci; Anita Mangia; Giovanni Simone; Nicola Silvestris; Amalia Azzariti
Journal:  Oncotarget       Date:  2017-02-07
  4 in total

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