Literature DB >> 24913358

Qualitative analysis of barriers and facilitators encountered by HIV patients in an ART adherence programme.

Isabelle Krummenacher1, Brenda Spencer, Sophie Du Pasquier, Olivier Bugnon, Matthias Cavassini, Marie P Schneider.   

Abstract

BACKGROUND: Medication adherence is a complex, dynamic and changing behaviour that is affected by a variety of factors, including the patient's beliefs and life circumstances. Studies have highlighted barriers to medication adherence (e.g., unmanaged side effects or a lack of social support), as well as facilitators of medication adherence (e.g., technical simplicity of treatment and psychological acceptance of the disease). Since August 2004, in Lausanne (Switzerland), physicians have referred patients who are either experiencing or are at risk of experiencing problems with their HIV antiretroviral treatment (ART) to a routine interdisciplinary ART adherence programme. This programme consists of multifactorial intervention including electronic drug monitoring (MEMS™).
OBJECTIVE: This study's objective was to identify the barriers and facilitators encountered by HIV patients with suboptimal medication adherence (≤90 % adherence over the study period).
SETTING: The community pharmacy of the Department of Ambulatory Care and Community Medicine in Lausanne (Switzerland).
METHOD: The study consisted of a retrospective, qualitative, thematic content analysis of pharmacists' notes that were taken during semi-structured interviews with patients and conducted as part of the ART adherence programme between August 2004 and May 2008. MAIN OUTCOME MEASURE: Barriers and facilitators encountered by HIV patients.
RESULTS: Barriers to and facilitators of adherence were identified for the 17 included patients. These factors fell into three main categories: (1) cognitive, emotional and motivational; (2) environmental, organisational and social; and (3) treatment and disease.
CONCLUSION: The pharmacists' notes revealed that diverse barriers and facilitators were discussed during medication adherence interviews. Indeed, the results showed that the 17 non-adherent patients encountered barriers and benefited from facilitators. Therefore, pharmacists should inquire about all factors, regardless of whether they have a negative or a positive impact on medication adherence, and should consider all dimensions of patient adherence. The simultaneous strengthening of facilitators and better management of barriers may allow healthcare providers to tailor care to a patient's specific needs and support each individual patient in improving his medication-related behaviour.

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Year:  2014        PMID: 24913358     DOI: 10.1007/s11096-014-9930-0

Source DB:  PubMed          Journal:  Int J Clin Pharm


  19 in total

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Authors:  Sigrid C J M Vervoort; Jan C C Borleffs; Andy I M Hoepelman; Mieke H F Grypdonck
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2.  Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study.

Authors:  Tracy R Glass; Sabina De Geest; Rainer Weber; Pietro L Vernazza; Martin Rickenbach; Hansjakob Furrer; Enos Bernasconi; Matthias Cavassini; Bernard Hirschel; Manuel Battegay; Heiner C Bucher
Journal:  J Acquir Immune Defic Syndr       Date:  2006-03       Impact factor: 3.731

3.  Predictive value of adherence in patients starting highly active antiretroviral treatment for HIV infection.

Authors:  T Wagels; R Amiet; M Battegay; A C Guex; M Opravil; P L Vernazza
Journal:  Swiss Med Wkly       Date:  2004-11-13       Impact factor: 2.193

4.  Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens.

Authors:  K J Roberts
Journal:  AIDS Patient Care STDS       Date:  2000-03       Impact factor: 5.078

5.  Barriers to antiretroviral adherence among HIV-infected adults.

Authors:  D A Murphy; K J Roberts; D J Martin; W Marelich; D Hoffman
Journal:  AIDS Patient Care STDS       Date:  2000-01       Impact factor: 5.078

6.  Adherence to HAART: processes explaining adherence behavior in acceptors and non-acceptors.

Authors:  Sigrid C J M Vervoort; Mieke H F Grypdonck; Annelies de Grauwe; Andy I M Hoepelman; Jan C C Borleffs
Journal:  AIDS Care       Date:  2009-04

7.  Experiences and perceptions of patients with 100% adherence to highly active antiretroviral therapy: a qualitative study.

Authors:  Mohsin Sidat; Christopher Fairley; Jeffrey Grierson
Journal:  AIDS Patient Care STDS       Date:  2007-07       Impact factor: 5.078

Review 8.  Correlates and predictors of adherence to highly active antiretroviral therapy: overview of published literature.

Authors:  Adriana Ammassari; Maria Paola Trotta; Rita Murri; Francesco Castelli; Pasquale Narciso; Pasquale Noto; Jacopo Vecchiet; Antonella D'Arminio Monforte; Albert W Wu; Andrea Antinori
Journal:  J Acquir Immune Defic Syndr       Date:  2002-12-15       Impact factor: 3.731

9.  Adherence to medication treatment: a qualitative study of facilitators and barriers among a diverse sample of HIV+ men and women in four US cities.

Authors:  Robert H Remien; A Elizabeth Hirky; Mallory O Johnson; Lance S Weinhardt; David Whittier; Giang Minh Le
Journal:  AIDS Behav       Date:  2003-03

Review 10.  Factors that influence the medication decision making of persons with HIV/AIDS: a taxonomic exploration.

Authors:  Cynthia K Russell; Sheila M Bunting; Marshall Graney; Margaret T Hartig; Patricia Kisner; Brian Brown
Journal:  J Assoc Nurses AIDS Care       Date:  2003 Jul-Aug       Impact factor: 1.354

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  4 in total

1.  Reasons for not starting antiretroviral therapy in HIV-1-infected individuals: a changing landscape.

Authors:  Jan Fehr; Dunja Nicca; Jean-Christophe Goffard; David Haerry; Michael Schlag; Vasileios Papastamopoulos; Andy Hoepelman; Athanasius Skoutelis; Ruth Diazaraque; Bruno Ledergerber
Journal:  Infection       Date:  2016-03-16       Impact factor: 3.553

2.  Noncompliance in people living with HIV: accuracy of defining characteristics of the nursing diagnosis1.

Authors:  Richardson Augusto Rosendo da Silva; Mayara Mirna do Nascimento Costa; Vinicius Lino de Souza; Bárbara Coeli Oliveira da Silva; Cristiane da Silva Costa; Itaísa Fernandes Cardoso de Andrade
Journal:  Rev Lat Am Enfermagem       Date:  2017-10-30

Review 3.  The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis.

Authors:  Haochu Li; Gifty Marley; Wei Ma; Chongyi Wei; Mellanye Lackey; Qingyan Ma; Françoise Renaud; Marco Vitoria; Rachel Beanland; Meg Doherty; Joseph D Tucker
Journal:  AIDS Behav       Date:  2017-02

4.  Interdisciplinary Medication Adherence Program: The Example of a University Community Pharmacy in Switzerland.

Authors:  Mélanie Lelubre; Susan Kamal; Noëllie Genre; Jennifer Celio; Séverine Gorgerat; Denise Hugentobler Hampai; Aline Bourdin; Jerôme Berger; Olivier Bugnon; Marie Schneider
Journal:  Biomed Res Int       Date:  2016-01-10       Impact factor: 3.411

  4 in total

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