Literature DB >> 24909859

Dual pH-triggered multistage drug delivery systems based on host-guest interaction-associated polymeric nanogels.

Minghui Zan1, Junjie Li, Shizhong Luo, Zhishen Ge.   

Abstract

The polymeric nanogels were constructed via host-guest interactions for dual pH-triggered multistage drug delivery, which showed tumor acidity-triggered nanogel reorganization into smaller nanoparticles for deep tissue penetration, high-efficiency cellular uptake, and intracellular endo-lysosomal pH-responsive drug release.

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Year:  2014        PMID： 24909859     DOI： 10.1039/c4cc03120b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Functional polymeric dialdehyde dextrin network capped mesoporous silica nanoparticles for pH/GSH dual-controlled drug release.

Authors:  Chao Chen; Wen Sun; Wenji Yao; Yibing Wang; Hanjie Ying; Ping Wang
Journal:  RSC Adv       Date:  2018-06-07       Impact factor: 4.036

2.  Utilizing G2/M retention effect to enhance tumor accumulation of active targeting nanoparticles.

Authors:  Guanlian Hu; Xingli Cun; Shaobo Ruan; Kairong Shi; Yang Wang; Qifang Kuang; Chuan Hu; Wei Xiao; Qin He; Huile Gao
Journal:  Sci Rep       Date:  2016-06-08       Impact factor: 4.379

Review 3.  Progress and perspectives on targeting nanoparticles for brain drug delivery.

Authors:  Huile Gao
Journal:  Acta Pharm Sin B       Date:  2016-06-14       Impact factor: 11.413

4.  Peptide mediated active targeting and intelligent particle size reduction-mediated enhanced penetrating of fabricated nanoparticles for triple-negative breast cancer treatment.

Authors:  Guanlian Hu; Xingli Chun; Yang Wang; Qin He; Huile Gao
Journal:  Oncotarget       Date:  2015-12-01

5.  Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy.

Authors:  Chia-Chian Hung; Wen-Chia Huang; Yi-Wen Lin; Ting-Wei Yu; Hsin-Hung Chen; Sung-Chyr Lin; Wen-Hsuan Chiang; Hsin-Cheng Chiu
Journal:  Theranostics       Date:  2016-01-01       Impact factor: 11.556

6.  Tumor Microenvironment Targeted Nanotherapy.

Authors:  Clara Fernandes; Divya Suares; Mayur C Yergeri
Journal:  Front Pharmacol       Date:  2018-10-31       Impact factor: 5.810

Review 7.  Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.

Authors:  Wei Wu; Li Luo; Yi Wang; Qi Wu; Han-Bin Dai; Jian-Shu Li; Colm Durkan; Nan Wang; Gui-Xue Wang
Journal:  Theranostics       Date:  2018-04-30       Impact factor: 11.556

8.  Matrix Metalloproteinase-sensitive Multistage Nanogels Promote Drug Transport in 3D Tumor Model.

Authors:  Gregor Nagel; Ana Sousa-Herves; Stefanie Wedepohl; Marcelo Calderón
Journal:  Theranostics       Date:  2020-01-01       Impact factor: 11.556
  8 in total

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