Tatiana Regina Ramos Nantes de Castilho1, Pedro Tortamano2, Juliana Marotti3, José Carlos Silva de Andrade1, Israel Chilvarquer4, Michel Eli Lipiec Ximenez5, Maria Teresa de Seixas Alves6. 1. Implantology Specialization Course, Fundação da Faculdade de Odontologia, School of Dentistry, University of São Paulo, São Paulo, Brazil. 2. Department of Prosthodontics, School of Dentistry, University of São Paulo, São Paulo, Brazil. 3. Department of Prosthodontics and Biomaterials, Faculty of Medicine, RWTH Aachen University, Aachen, Germany. 4. Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil. 5. Radiology Specialization Course, Associação Paulista dos Cirurgiões Dentistas-Jardim Paulista, São Paulo, Brazil. 6. Department of Pathology, Federal University of São Paulo, São Paulo, Brazil.
Abstract
PURPOSE: The aim of this prospective clinical study was to evaluate the clinical and histomorphometric data of newly formed bone tissue from fresh frozen human allograft in sinus lift surgery. PATIENTS AND METHODS: Thirty-three sinus lift procedures were performed in 20 patients, divided into two groups. The control group (n = 8) received autogenous bone from the mandibular ramus, and the experimental group (n = 12) received fresh frozen bone (FFB) allograft in chips. After 6 months, 52 implants were placed and 50 biopsies were collected for histomorphometric analysis. Cone beam computed tomography scans were performed at preoperative, immediate postoperative, and delayed postoperative time intervals to assess the degree of graft volume loss. RESULTS: There was no statistically significant difference between groups as regards degree of graft volume loss (p = .983), total bone area (p = .191), remaining particles (p = .348), and proportion of active osteoblasts (p = .867). There was a statistically significant difference in the vitality rate between the groups (p = .043). In both groups, all implants were clinically osseointegrated after 4 months. CONCLUSION: FFB allograft was shown to be a feasible substitute for autogenous bone graft in sinus lift surgery.
PURPOSE: The aim of this prospective clinical study was to evaluate the clinical and histomorphometric data of newly formed bone tissue from fresh frozen human allograft in sinus lift surgery. PATIENTS AND METHODS: Thirty-three sinus lift procedures were performed in 20 patients, divided into two groups. The control group (n = 8) received autogenous bone from the mandibular ramus, and the experimental group (n = 12) received fresh frozen bone (FFB) allograft in chips. After 6 months, 52 implants were placed and 50 biopsies were collected for histomorphometric analysis. Cone beam computed tomography scans were performed at preoperative, immediate postoperative, and delayed postoperative time intervals to assess the degree of graft volume loss. RESULTS: There was no statistically significant difference between groups as regards degree of graft volume loss (p = .983), total bone area (p = .191), remaining particles (p = .348), and proportion of active osteoblasts (p = .867). There was a statistically significant difference in the vitality rate between the groups (p = .043). In both groups, all implants were clinically osseointegrated after 4 months. CONCLUSION: FFB allograft was shown to be a feasible substitute for autogenous bone graft in sinus lift surgery.