Literature DB >> 24908291

Analysis of the released nuclear cytokine HMGB1 in human serum.

Haichao Wang1, Lin Zhao, Jianhua Li, Shu Zhu, Maggie Yeung.   

Abstract

A ubiquitous nuclear protein, the high-mobility group box 1 (HMGB1), is secreted by activated macrophages/monocytes and leaked passively from injured cells. HMGB1 functions as a mediator of infection- and injury-elicited inflammatory diseases. Here, we describe a semiquantitative immuno-blotting method to measure the released HMGB1 in human serum, in comparison with a commercially available HMGB1 ELISA technique.

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Year:  2014        PMID: 24908291     DOI: 10.1007/978-1-4939-0928-5_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  2 in total

Review 1.  Progress in Assays of HMGB1 Levels in Human Plasma-The Potential Prognostic Value in COVID-19.

Authors:  Michal Štros; Eva Volfová Polanská; Tereza Hlaváčová; Petr Skládal
Journal:  Biomolecules       Date:  2022-04-05

2.  High Mobility Group Box-1 Protein and Outcomes in Critically Ill Surgical Patients Requiring Open Abdominal Management.

Authors:  Michelle S Malig; Craig N Jenne; Chad G Ball; Derek J Roberts; Zhengwen Xiao; Andrew W Kirkpatrick
Journal:  Mediators Inflamm       Date:  2017-02-14       Impact factor: 4.711

  2 in total

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