| Literature DB >> 24905335 |
Kathryn Oostdik1, Kristy Lenz2, Jeffrey Nye3, Kristin Schelling4, Donald Yet5, Scott Bruski6, Joshua Strong7, Clint Buchanan8, Joel Sutton9, Jessica Linner10, Nicole Frazier11, Hays Young12, Learden Matthies13, Amber Sage14, Jeff Hahn15, Regina Wells16, Natasha Williams17, Monica Price18, Jody Koehler19, Melisa Staples20, Katie L Swango21, Carolyn Hill22, Karen Oyerly23, Wendy Duke24, Lesley Katzilierakis25, Martin G Ensenberger26, Jeanne M Bourdeau27, Cynthia J Sprecher28, Benjamin Krenke29, Douglas R Storts30.
Abstract
The original CODIS database based on 13 core STR loci has been overwhelmingly successful for matching suspects with evidence. Yet there remain situations that argue for inclusion of more loci and increased discrimination. The PowerPlex(®) Fusion System allows simultaneous amplification of the following loci: Amelogenin, D3S1358, D1S1656, D2S441, D10S1248, D13S317, Penta E, D16S539, D18S51, D2S1338, CSF1PO, Penta D, TH01, vWA, D21S11, D7S820, D5S818, TPOX, DYS391, D8S1179, D12S391, D19S433, FGA, and D22S1045. The comprehensive list of loci amplified by the system generates a profile compatible with databases based on either the expanded CODIS or European Standard Set (ESS) requirements. Developmental validation testing followed SWGDAM guidelines and demonstrated the quality and robustness of the PowerPlex(®) Fusion System across a number of variables. Consistent and high-quality results were compiled using data from 12 separate forensic and research laboratories. The results verify that the PowerPlex(®) Fusion System is a robust and reliable STR-typing multiplex suitable for human identification.Entities:
Keywords: Forensic science; PowerPlex(R); Short tandem repeat; Validation
Mesh：
Year: 2014 PMID： 24905335 DOI： 10.1016/j.fsigen.2014.04.013
Source DB: PubMed Journal: Forensic Sci Int Genet ISSN： 1872-4973 Impact factor: 4.882