Literature DB >> 24905161

Saying no to drugs: fasting protects hematopoietic stem cells from chemotherapy and aging.

Christopher Hine1, James R Mitchell2.   

Abstract

Aging and chemotherapeutics damage hematopoietic stem cells (HSCs), leading to dysregulation of asymmetric division and subsequent immunosuppression and blood-related diseases. In this issue, Cheng et al. (2014) use prolonged fasting as a medical intervention to decrease IGF-1/PKA signaling and protect HSCs against chemotherapeutic toxicity and promote rejuvenation.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24905161      PMCID： PMC4278638          DOI： 10.1016/j.stem.2014.05.016

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  9 in total

1.  Prevention of chemotherapy-induced anemia and thrombocytopenia by constant administration of stem cell factor.

Authors:  Monica Bartucci; Rosanna Dattilo; Daniela Martinetti; Matilde Todaro; Giuseppina Zapparelli; Antonio Di Virgilio; Mauro Biffoni; Ruggero De Maria; Ann Zeuner
Journal:  Clin Cancer Res       Date:  2011-08-25       Impact factor: 12.531

Review 2.  Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy.

Authors:  P Mauch; L Constine; J Greenberger; W Knospe; J Sullivan; J L Liesveld; H J Deeg
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-03-30       Impact factor: 7.038

3.  Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

Authors:  Wendy W Pang; Elizabeth A Price; Debashis Sahoo; Isabel Beerman; William J Maloney; Derrick J Rossi; Stanley L Schrier; Irving L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-28       Impact factor: 11.205

4.  Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.

Authors:  Chia-Wei Cheng; Gregor B Adams; Laura Perin; Min Wei; Xiaoying Zhou; Ben S Lam; Stefano Da Sacco; Mario Mirisola; David I Quinn; Tanya B Dorff; John J Kopchick; Valter D Longo
Journal:  Cell Stem Cell       Date:  2014-06-05       Impact factor: 24.633

5.  Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis.

Authors:  Zhi-Chun Ding; Xiaoyun Lu; Miao Yu; Henrique Lemos; Lei Huang; Phillip Chandler; Kebin Liu; Matthew Walters; Antoni Krasinski; Matthias Mack; Bruce R Blazar; Andrew L Mellor; David H Munn; Gang Zhou
Journal:  Cancer Res       Date:  2014-04-29       Impact factor: 12.701

6.  Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle.

Authors:  Isabel Beerman; Jun Seita; Matthew A Inlay; Irving L Weissman; Derrick J Rossi
Journal:  Cell Stem Cell       Date:  2014-05-08       Impact factor: 24.633

7.  BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.

Authors:  Eleni D Lagadinou; Alexander Sach; Kevin Callahan; Randall M Rossi; Sarah J Neering; Mohammad Minhajuddin; John M Ashton; Shanshan Pei; Valerie Grose; Kristen M O'Dwyer; Jane L Liesveld; Paul S Brookes; Michael W Becker; Craig T Jordan
Journal:  Cell Stem Cell       Date:  2013-01-17       Impact factor: 24.633

Review 8.  Benefits of short-term dietary restriction in mammals.

Authors:  Lauren T Robertson; James R Mitchell
Journal:  Exp Gerontol       Date:  2013-02-01       Impact factor: 4.032

9.  Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

Authors:  Lizzia Raffaghello; Changhan Lee; Fernando M Safdie; Min Wei; Federica Madia; Giovanna Bianchi; Valter D Longo
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-31       Impact factor: 11.205
  9 in total
  3 in total

1.  Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

Authors:  Irene Caffa; Vito D'Agostino; Patrizia Damonte; Debora Soncini; Michele Cea; Fiammetta Monacelli; Patrizio Odetti; Alberto Ballestrero; Alessandro Provenzani; Valter D Longo; Alessio Nencioni
Journal:  Oncotarget       Date:  2015-05-20

2.  Impact of Elimination or Reduction of Dietary Animal Proteins on Cancer Progression and Survival: Protocol of an Online Pilot Cohort Study.

Authors:  Anna Catany Ritter; Annarita Sabrina Egger; Jennifer Machacek; Rosa Aspalter
Journal:  JMIR Res Protoc       Date:  2016-07-29

3.  The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain.

Authors:  Jianhui Wang; Xiaorui Cheng; Xiaorui Zhang; Junping Cheng; Yiran Xu; Ju Zeng; Wenxia Zhou; Yongxiang Zhang
Journal:  Oncotarget       Date:  2016-05-10
  3 in total

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