| Literature DB >> 24905075 |
Chandra Bhushan Tripathi1, Santanu Mukherjee.
Abstract
The first catalytic enantioselective iodoaminocyclization of β,γ-unsaturated hydrazones has been developed with the help of a trans-1,2-diaminocyclohexane-derived bifunctional thiourea catalyst and allows for the direct access to Δ(2)-pyrazolines containing a quaternary stereogenic center in high yield with good enantioselectivity (up to 95% yield and 95:5 er).Entities:
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Year: 2014 PMID： 24905075 DOI： 10.1021/ol5013982
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005