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Literature DB >> 24903622

Brugada phenocopy in concomitant ethanol and heroin overdose.

Mehdi Rambod¹, Sherif Elhanafi, Debabrata Mukherjee.

Abstract

Brugada phenocopy describes conditions with Brugada-like ECG pattern but without true congenital Brugada syndrome. We report a case of 44-year-old man with no known medical history who presented with loss of consciousness. Toxicology screening was positive for opiates and high serum alcohol level. His initial ECG showed Brugada type 1 pattern which resolved after several hours of observation and treatment with continuous naloxone infusion. Patient regained his consciousness and disclosed heroin abuse and drinking alcohol. This case highlights the heroin overdose as a possible cause of Brugada phenocopy.

Entities: Chemical Disease Species

Keywords: Brugada syndrome; electrocardiography; electrophysiology; noninvasive techniques

Mesh：

Substances：

Year: 2014 PMID： 24903622 PMCID： PMC6931511 DOI： 10.1111/anec.12171

Source DB: PubMed Journal: Ann Noninvasive Electrocardiol ISSN： 1082-720X Impact factor: 1.468

12 in total

1. Overdose of cyclic antidepressants and the Brugada syndrome.

Authors: Dany Goldgran-Toledano; Georgios Sideris; Jean-Philippe Kevorkian
Journal: N Engl J Med Date: 2002-05-16 Impact factor: 91.245

2. Brugada syndrome unmasked by sodium channel blockade.

Authors: Rajesh S Badani; K Sharada; Hygriv B Rao; Narasimhan C
Journal: Indian Heart J Date: 2006 Nov-Dec

3. Brugada phenocopy clinical reproducibility demonstrated by recurrent hypokalemia.

Authors: Natalia R Genaro; Daniel D Anselm; Nahuel Cervino; Ariel O Estevez; Carlos Perona; Alejandro M Villamil; Ruben Kervorkian; Adrian Baranchuk
Journal: Ann Noninvasive Electrocardiol Date: 2013-10-23 Impact factor: 1.468

Review 4. Brugada phenocopy: new terminology and proposed classification.

Authors: Adrian Baranchuk; Timothy Nguyen; Min Hyung Ryu; Francisco Femenía; Wojciech Zareba; Arthur A M Wilde; Wataru Shimizu; Pedro Brugada; Andrés R Pérez-Riera
Journal: Ann Noninvasive Electrocardiol Date: 2012-08-13 Impact factor: 1.468

5. Brugada phenocopy: redefinition and updated classification.

Authors: Daniel D Anselm; Adrian Baranchuk
Journal: Am J Cardiol Date: 2013-02-01 Impact factor: 2.778

6. The effect of heroin and multiple drug abuse on the electrocardiogram.

Authors: J Lipski; B Stimmel; E Donoso
Journal: Am Heart J Date: 1973-11 Impact factor: 4.749

7. National trends in pharmaceutical opioid related overdose deaths compared to other substance related overdose deaths: 1999-2009.

Authors: Susan Calcaterra; Jason Glanz; Ingrid A Binswanger
Journal: Drug Alcohol Depend Date: 2013-01-05 Impact factor: 4.492

8. Sustained monomorphic ventricular tachycardia in a patient with Brugada syndrome.

Authors: M Shimada; T Miyazaki; S Miyoshi; K Soejima; S Hori; H Mitamura; S Ogawa
Journal: Jpn Circ J Date: 1996-06

9. Ethanol inhibition of Ca2+ and Na+ currents in the guinea-pig heart.

Authors: Y Habuchi; T Furukawa; H Tanaka; L L Lu; J Morikawa; M Yoshimura
Journal: Eur J Pharmacol Date: 1995-01-13 Impact factor: 4.432

10. Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report.

Authors: Antonio Bayés de Luna; Josep Brugada; Adrian Baranchuk; Martin Borggrefe; Guenter Breithardt; Diego Goldwasser; Pier Lambiase; Andrés Pérez Riera; Javier Garcia-Niebla; Carlos Pastore; Giuseppe Oreto; William McKenna; Wojciech Zareba; Ramon Brugada; Pedro Brugada
Journal: J Electrocardiol Date: 2012-09 Impact factor: 1.438

6 in total

Brugada phenocopy in concomitant ethanol and heroin overdose.

1. Overdose of cyclic antidepressants and the Brugada syndrome.

2. Brugada syndrome unmasked by sodium channel blockade.

3. Brugada phenocopy clinical reproducibility demonstrated by recurrent hypokalemia.

Review 4. Brugada phenocopy: new terminology and proposed classification.

5. Brugada phenocopy: redefinition and updated classification.

6. The effect of heroin and multiple drug abuse on the electrocardiogram.

7. National trends in pharmaceutical opioid related overdose deaths compared to other substance related overdose deaths: 1999-2009.

8. Sustained monomorphic ventricular tachycardia in a patient with Brugada syndrome.

9. Ethanol inhibition of Ca2+ and Na+ currents in the guinea-pig heart.

10. Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report.

1. Brugada phenocopy: morphological classification and importance of provocative testing.

2. Response to: Brugada phenocopy: morphological classification and importance of provocative testing.

3. Brugada syndrome, Brugada phenocopy or none?

4. Effect of Heroin on Electrocardiographic Parameters.

5. Brugada phenocopy in a patient with acute pulmonary embolism presenting with recurrent syncope.

6. Brugada Phenocopy Induced by Recreational Drug Use.