Literature DB >> 24903499

[Imaging diagnostics of bone sarcomas].

J A Krämer1, R Gübitz, L Beck, W Heindel, V Vieth.   

Abstract

BACKGROUND: Bone tumors and especially bone sarcomas are rare lesions of the skeletal system in comparison to the much more frequently occurring bone metastases. Despite the relative rarity they are important differential diagnoses of bone lesions.
OBJECTIVE: The aim of this article is to give the reader an insight into the fundamentals of the primary imaging of bone sarcomas and to illustrate this with the help of two examples (e.g. osteosarcoma and chondrosarcoma).
RESULTS: The foundation of the imaging of bone sarcomas is the radiograph in two planes. This method delivers important information on bone tumors. This information should be analyzed with the help of the Lodwick classification, the configuration of periosteal reactions and a possible reaction of the cortex. A possible tumor matrix and the localization within the skeleton or within long bones also provide important information for differential diagnostic delimitation. Magnetic resonance imaging (MRI) with specific adapted bone tumor sequences allows an exact local staging of a bone sarcoma. In addition to local imaging a compartmental MRI which illustrates the entire extent of tumor-bearing bone and the adjacent joints should be performed to rule out possible skip lesions. The most common distant metastases of osteosarcoma and chondrosarcoma occur in the lungs; therefore, a computed tomography (CT) of the chest is part of staging. Other imaging methods, such as CT of the tumor, positron emission tomography CT (PET-CT), bone scan and whole body MRI supplement the imaging depending on tumor type.

Entities:  

Mesh:

Year:  2014        PMID: 24903499     DOI: 10.1007/s00113-013-2470-6

Source DB:  PubMed          Journal:  Unfallchirurg        ISSN: 0177-5537            Impact factor:   1.000


  20 in total

Review 1.  Osteosarcoma: anatomic and histologic variants.

Authors:  Michael J Klein; Gene P Siegal
Journal:  Am J Clin Pathol       Date:  2006-04       Impact factor: 2.493

Review 2.  Imaging characteristics of primary osteosarcoma: nonconventional subtypes.

Authors:  Gail Yarmish; Michael J Klein; Jonathan Landa; Robert A Lefkowitz; Sinchun Hwang
Journal:  Radiographics       Date:  2010-10       Impact factor: 5.333

3.  Bone scanning in osseous metastatic disease.

Authors:  R E O'Mara
Journal:  JAMA       Date:  1974-09-30       Impact factor: 56.272

Review 4.  Radiographic evaluation of solitary bone lesions.

Authors:  M E Kricun
Journal:  Orthop Clin North Am       Date:  1983-01       Impact factor: 2.472

5.  Determining growth rates of focal lesions of bone from radiographs.

Authors:  G S Lodwick; A J Wilson; C Farrell; P Virtama; F Dittrich
Journal:  Radiology       Date:  1980-03       Impact factor: 11.105

6.  Screening for bone metastases: whole-body MRI using a 32-channel system versus dual-modality PET-CT.

Authors:  Gerwin P Schmidt; Stefan O Schoenberg; Rupert Schmid; Robert Stahl; Reinhold Tiling; Christoph R Becker; Maximilian F Reiser; Andrea Baur-Melnyk
Journal:  Eur Radiol       Date:  2006-09-02       Impact factor: 5.315

Review 7.  Imaging of primary malignant bone tumors (nonhematological).

Authors:  Prabhakar Rajiah; Hakan Ilaslan; Murali Sundaram
Journal:  Radiol Clin North Am       Date:  2011-09-21       Impact factor: 2.303

8.  [MRI morphology of bone tumors and tumor-like lesions].

Authors:  R Erlemann
Journal:  Radiologe       Date:  2010-01       Impact factor: 0.635

9.  A system for the surgical staging of musculoskeletal sarcoma.

Authors:  W F Enneking; S S Spanier; M A Goodman
Journal:  Clin Orthop Relat Res       Date:  1980 Nov-Dec       Impact factor: 4.176

10.  Osteosarcoma, chondrosarcoma, and Ewing's sarcoma: National Cancer Data Base Report.

Authors:  Timothy A Damron; William G Ward; Andrew Stewart
Journal:  Clin Orthop Relat Res       Date:  2007-06       Impact factor: 4.176

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