Literature DB >> 24903477

Biocompatible, chimeric peptide-condensed supramolecular nanoparticles for tumor cell-specific siRNA delivery and gene silencing.

Hangxiang Wang1, Wei Chen, Haiyang Xie, Xuyong Wei, Shengyong Yin, Lin Zhou, Xiao Xu, Shusen Zheng.   

Abstract

Chimeric peptides composed of arginine-rich RNA-binding and tumor cell-targeting motifs have been employed to condense siRNA to form supramolecular nanoparticles via electrostatic associations and deliver siRNA agents in a tumor cell-specific manner.

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Year:  2014        PMID: 24903477     DOI: 10.1039/c4cc01061b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

1.  Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery.

Authors:  Xueqin Huang; Robert J Lee; Yuhang Qi; Yujing Li; Jiahui Lu; Qingfan Meng; Lesheng Teng; Jing Xie
Journal:  Oncotarget       Date:  2017-05-30

2.  A nanomedicine approach enables co-delivery of cyclosporin A and gefitinib to potentiate the therapeutic efficacy in drug-resistant lung cancer.

Authors:  Weidong Han; Linlin Shi; Lulu Ren; Liqian Zhou; Tongyu Li; Yiting Qiao; Hangxiang Wang
Journal:  Signal Transduct Target Ther       Date:  2018-06-22

3.  Novel fusion peptide-mediated siRNA delivery using self-assembled nanocomplex.

Authors:  Yeong Chae Ryu; Kyung Ah Kim; Byoung Choul Kim; Hui-Min David Wang; Byeong Hee Hwang
Journal:  J Nanobiotechnology       Date:  2021-02-12       Impact factor: 10.435

Review 4.  Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications.

Authors:  Christopher D Spicer; Coline Jumeaux; Bakul Gupta; Molly M Stevens
Journal:  Chem Soc Rev       Date:  2018-05-21       Impact factor: 54.564

5.  Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma.

Authors:  Hangxiang Wang; Liqian Zhou; Ke Xie; Jiaping Wu; Penghong Song; Haiyang Xie; Lin Zhou; Jialin Liu; Xiao Xu; Youqing Shen; Shusen Zheng
Journal:  Theranostics       Date:  2018-06-24       Impact factor: 11.556

  5 in total

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