| Literature DB >> 24900285 |
Kenji Watanabe1, Hiroaki Kitagishi1, Koji Kano1.
Abstract
All fundamental data about binding of the cyanide to a supramolecular complex composed of a per-O-methylated β-cyclodextrin dimer having an imidazole linker (Im3CD) and an anionic ferric porphyrin (Fe((III))TPPS) indicate that the Fe((III))TPPS/Im3CD complex is much better as an cyanide receptor in vivo than hydroxocobalamin, whose cyanide binding ability is lowered by its strong binding to serum proteins in the blood.Entities:
Keywords: Cyclodextrin dimer; cyanide binding; cyanide receptor; ferric porphyrin; supramolecules
Year: 2011 PMID: 24900285 PMCID: PMC4018087 DOI: 10.1021/ml200231x
Source DB: PubMed Journal: ACS Med Chem Lett ISSN: 1948-5875 Impact factor: 4.345