Literature DB >> 24899457

Eliminating tuberculosis one neighborhood at a time.

J Peter Cegielski1, David E Griffith, Paul K McGaha, Melanie Wolfgang, Celia B Robinson, Patricia A Clark, Willis L Hassell, Valerie A Robison, Kerfoot P Walker, Charles Wallace.   

Abstract

OBJECTIVES: We evaluated a strategy for preventing tuberculosis (TB) in communities most affected by it.
METHODS: In 1996, we mapped reported TB cases (1985-1995) and positive tuberculin skin test (TST) reactors (1993-1995) in Smith County, Texas. We delineated the 2 largest, densest clusters, identifying 2 highest-incidence neighborhoods (180 square blocks, 3153 residents). After extensive community preparation, trained health care workers went door-to-door offering TST to all residents unless contraindicated. TST-positive individuals were escorted to a mobile clinic for radiography, clinical evaluation, and isoniazid preventive treatment (IPT) as indicated. To assess long-term impact, we mapped all TB cases in Smith County during the equivalent time period after the project.
RESULTS: Of 2258 eligible individuals, 1291 (57.1%) were tested, 229 (17.7%) were TST positive, and 147 were treated. From 1996 to 2006, there were no TB cases in either project neighborhood, in contrast with the preintervention decade and the continued occurrence of TB in the rest of Smith County.
CONCLUSIONS: Targeting high-incidence neighborhoods for active, community-based screening and IPT may hasten TB elimination in the United States.

Entities:  

Year:  2014        PMID: 24899457      PMCID: PMC5319210          DOI: 10.2105/AJPH.2012.300781r

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  15 in total

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Authors:  C Robert Horsburgh; Stefan Goldberg; James Bethel; Shande Chen; Paul W Colson; Yael Hirsch-Moverman; Stephen Hughes; Robin Shrestha-Kuwahara; Timothy R Sterling; Kirsten Wall; Paul Weinfurter
Journal:  Chest       Date:  2009-09-30       Impact factor: 9.410

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Journal:  MMWR Recomm Rep       Date:  1992-04-17

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Authors:  Patrick K Moonan; Manuel Bayona; Teresa N Quitugua; Joseph Oppong; Denise Dunbar; Kenneth C Jost; Gerry Burgess; Karan P Singh; Stephen E Weis
Journal:  Int J Health Geogr       Date:  2004-10-13       Impact factor: 3.918

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  1 in total

Review 1.  Where is tuberculosis transmission happening? Insights from the literature, new tools to study transmission and implications for the elimination of tuberculosis.

Authors:  Sara C Auld; N Sarita Shah; Ted Cohen; Neil A Martinson; Neel R Gandhi
Journal:  Respirology       Date:  2018-06-05       Impact factor: 6.424

  1 in total

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