OBJECTIVES: To evaluate the frequency of obesity in postmenopausal women and assess the potential effects of increased body mass index (BMI) on lipoprotein profile and on risk factors for arterial hypertension and diabetes. DESIGN: A cross-sectional study was conducted with 5027 postmenopausal Brazilian women. Analyses were performed of BMI and cardiovascular factors (systemic blood pressure [BP], total cholesterol, low-density lipoprotein, high-density lipoprotein [HDL-C], triglyceride, and fast glucose). The statistical analysis included the chi-square and Mann-Whitney tests. The significance level was set at 5%. RESULTS: Obesity (BMI >30) in our study characterized approximately 30% of the 5027 postmenopausal women. The comparison of patients with normal BMI and those with high BMI showed that high BMI had a significant negative effect on BP, as evidenced by the increased frequency of hypertension in overweight and obese patients (>25) (p < 0.001), that it also negatively and significantly affected triglyceride (p < 0.001) and fast glucose levels (p < 0.001), and that it was linked significantly to low levels of HDL-C. CONCLUSION: Our data showed the high frequency of obesity in our population and of the cardiovascular risks (glucose, systemic arterial hypertension, and low HDL-C) associated with high BMI.
OBJECTIVES: To evaluate the frequency of obesity in postmenopausal women and assess the potential effects of increased body mass index (BMI) on lipoprotein profile and on risk factors for arterial hypertension and diabetes. DESIGN: A cross-sectional study was conducted with 5027 postmenopausal Brazilian women. Analyses were performed of BMI and cardiovascular factors (systemic blood pressure [BP], total cholesterol, low-density lipoprotein, high-density lipoprotein [HDL-C], triglyceride, and fast glucose). The statistical analysis included the chi-square and Mann-Whitney tests. The significance level was set at 5%. RESULTS:Obesity (BMI >30) in our study characterized approximately 30% of the 5027 postmenopausal women. The comparison of patients with normal BMI and those with high BMI showed that high BMI had a significant negative effect on BP, as evidenced by the increased frequency of hypertension in overweight and obesepatients (>25) (p < 0.001), that it also negatively and significantly affected triglyceride (p < 0.001) and fast glucose levels (p < 0.001), and that it was linked significantly to low levels of HDL-C. CONCLUSION: Our data showed the high frequency of obesity in our population and of the cardiovascular risks (glucose, systemic arterial hypertension, and low HDL-C) associated with high BMI.
Authors: Tatiana Dias de Carvalho; Alex Rey Norberto; Fernando Rocha Oliveira; Laercio da Silva Paiva; Edmund Chada Baracat; José Maria Soares Júnior; Luiz Carlos Marques Vanderlei; Isabel Cristina Esposito Sorpreso Journal: Rev Assoc Med Bras (1992) Date: 2022-05-13 Impact factor: 1.712
Authors: Adna Thaysa Marcial da Silva; Camila Lohmann Menezes; Edige Felipe de Sousa Santos; Paulo Francisco Ramos Margarido; José Maria Soares; Edmund Chada Baracat; Luiz Carlos de Abreu; Isabel Cristina Esposito Sorpreso Journal: BMC Womens Health Date: 2018-01-05 Impact factor: 2.809
Authors: Isabel Cristina Esposito Sorpreso; Francisco Winter Dos Santos Figueiredo; José Lucas Souza Ramos; Lea Tami Suzuki Zuchelo; Fernando Adami; Edmund Chada Baracat; José Maria Soares Júnior Journal: BMC Public Health Date: 2021-03-16 Impact factor: 3.295