| Literature DB >> 24898063 |
Manpreet Bhatti1, Timothy D McHugh, Lilia Milanesi, Salvador Tomas.
Abstract
A self-assembled nanoparticle containing a photosensitizer and a Trojan-horse moiety (cholesterol), binds an anti-TB pro-drug and increases 1000-fold its activity against mycobacteria. These minimalist constructs will allow development of economically viable, efficient drug preparations for the treatment of drug-resistant TB infections.Entities:
Mesh：
Substances：
Year: 2014 PMID： 24898063 DOI： 10.1039/c4cc00349g
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222