Literature DB >> 24896536

IL-6 strikes a balance in metabolic inflammation.

Anthony J Covarrubias1, Tiffany Horng2.   

Abstract

Interleukin-6 (IL-6) is a pleiotropic cytokine that exerts either proinflammatory or anti-inflammatory effects and is implicated in diverse settings, including obesity, exercise, arthritis, and colitis. A new study shows that modulation of macrophage activation by IL-6 maintains glucose homeostasis in diet-induced obesity while limiting inflammation in endotoxemia (Mauer et al., 2014).
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24896536      PMCID： PMC4103792          DOI： 10.1016/j.cmet.2014.05.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  10 in total

Review 1.  Inflammatory mechanisms in obesity.

Authors:  Margaret F Gregor; Gökhan S Hotamisligil
Journal:  Annu Rev Immunol       Date:  2011       Impact factor: 28.527

2.  Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis.

Authors:  Bente K Pedersen; Mark A Febbraio
Journal:  J Appl Physiol (1985)       Date:  2006-10-26

3.  Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue.

Authors:  Aliki Kosteli; Eiji Sugaru; Guenter Haemmerle; Jayne F Martin; Jason Lei; Rudolf Zechner; Anthony W Ferrante
Journal:  J Clin Invest       Date:  2010-09-27       Impact factor: 14.808

Review 4.  Macrophage-mediated inflammation in metabolic disease.

Authors:  Ajay Chawla; Khoa D Nguyen; Y P Sharon Goh
Journal:  Nat Rev Immunol       Date:  2011-10-10       Impact factor: 53.106

Review 5.  Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications.

Authors:  Nicolas J Pillon; Philip J Bilan; Lisbeth N Fink; Amira Klip
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-12-31       Impact factor: 4.310

Review 6.  The pro- and anti-inflammatory properties of the cytokine interleukin-6.

Authors:  Jürgen Scheller; Athena Chalaris; Dirk Schmidt-Arras; Stefan Rose-John
Journal:  Biochim Biophys Acta       Date:  2011-02-04

7.  Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice.

Authors:  Ingrid Wernstedt; Amanda Edgley; Anna Berndtsson; Jenny Fäldt; Göran Bergström; Ville Wallenius; John-Olov Jansson
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2006-09       Impact factor: 3.619

8.  Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice.

Authors:  Stephan Wueest; Flurin Item; Christina N Boyle; Paulin Jirkof; Nikola Cesarovic; Helga Ellingsgaard; Marianne Böni-Schnetzler; Katharina Timper; Margarete Arras; Marc Y Donath; Thomas A Lutz; Eugen J Schoenle; Daniel Konrad
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2014-04-02       Impact factor: 3.619

9.  Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.

Authors:  Khoa D Nguyen; Yifu Qiu; Xiaojin Cui; Y P Sharon Goh; Julia Mwangi; Tovo David; Lata Mukundan; Frank Brombacher; Richard M Locksley; Ajay Chawla
Journal:  Nature       Date:  2011-11-20       Impact factor: 49.962

10.  Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.

Authors:  Jan Mauer; Bhagirath Chaurasia; Julia Goldau; Merly C Vogt; Johan Ruud; Khoa D Nguyen; Sebastian Theurich; A Christine Hausen; Joel Schmitz; Hella S Brönneke; Emma Estevez; Tamara L Allen; Andrea Mesaros; Linda Partridge; Mark A Febbraio; Ajay Chawla; F Thomas Wunderlich; Jens C Brüning
Journal:  Nat Immunol       Date:  2014-03-30       Impact factor: 25.606
  10 in total
  15 in total

1.  Lowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model.

Authors:  Reilly T Enos; Kandy T Velázquez; Jamie L McClellan; Taryn L Cranford; Michael D Walla; E Angela Murphy
Journal:  Nutr Res       Date:  2015-04-11       Impact factor: 3.315

2.  Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice.

Authors:  Nancy M Lainez; Djurdjica Coss
Journal:  Neuroendocrinology       Date:  2019-01-10       Impact factor: 4.914

3.  A novel cobiotic-based preventive approach against high-fat diet-induced adiposity, nonalcoholic fatty liver and gut derangement in mice.

Authors:  D P Singh; P Khare; J Zhu; K K Kondepudi; J Singh; R K Baboota; R K Boparai; R Khardori; K Chopra; M Bishnoi
Journal:  Int J Obes (Lond)       Date:  2015-09-23       Impact factor: 5.095

4.  ILDR2-Fc Is a Novel Regulator of Immune Homeostasis and Inducer of Antigen-Specific Immune Tolerance.

Authors:  Joseph R Podojil; Iris Hecht; Ming-Yi Chiang; Ilan Vaknin; Inbal Barbiro; Amit Novik; Eyal Neria; Galit Rotman; Stephen D Miller
Journal:  J Immunol       Date:  2018-02-05       Impact factor: 5.422

Review 5.  Obesity, Neuroinflammation, and Reproductive Function.

Authors:  Nancy M Lainez; Djurdjica Coss
Journal:  Endocrinology       Date:  2019-11-01       Impact factor: 4.736

6.  Origin and Function of Stress-Induced IL-6 in Murine Models.

Authors:  Hua Qing; Reina Desrouleaux; Kavita Israni-Winger; Yann S Mineur; Nia Fogelman; Cuiling Zhang; Saleh Rashed; Noah W Palm; Rajita Sinha; Marina R Picciotto; Rachel J Perry; Andrew Wang
Journal:  Cell       Date:  2020-06-30       Impact factor: 41.582

7.  An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Report.

Authors:  Grace E Weber; Katherine A Koenig; Maria Khrestian; Yvonne Shao; Elizabeth D Tuason; Marie Gramm; Dennis Lal; James B Leverenz; Lynn M Bekris
Journal:  J Immunol       Date:  2020-01-20       Impact factor: 5.422

Review 8.  Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity.

Authors:  Sonia Kiran; Vijay Kumar; Santosh Kumar; Robert L Price; Udai P Singh
Journal:  Cells       Date:  2021-04-24       Impact factor: 6.600

Review 9.  Role of pro- and anti-inflammatory phenomena in the physiopathology of type 2 diabetes and obesity.

Authors:  Luciano Pirola; José Candido Ferraz
Journal:  World J Biol Chem       Date:  2017-05-26

10.  Oxygen Tension Strongly Influences Metabolic Parameters and the Release of Interleukin-6 of Human Amniotic Mesenchymal Stromal Cells In Vitro.

Authors:  Asmita Banerjee; Andrea Lindenmair; Ralf Steinborn; Sergiu Dan Dumitrescu; Simone Hennerbichler; Andrey V Kozlov; Heinz Redl; Susanne Wolbank; Adelheid Weidinger
Journal:  Stem Cells Int       Date:  2018-10-28       Impact factor: 5.443
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.