| Literature DB >> 24894556 |
Chao Wang1, Jing Yang1, Ping Zhao1, Qi Zhou1, Zhinan Mei1, Guangzhong Yang1, Xinzhou Yang2, Yunjiang Feng3.
Abstract
Bioassay-guided phytochemical investigation of the EtOAc fraction from the leaves of a Chinese medicinal herb, Eucalyptus citriodora Hook, resulted in the isolation of a new compound rhodomyrtosone E (1), along with 12 known compounds (2-13). The structure of the new compound was established by 1D and 2D NMR, MS data and X-ray crystallographic analysis. Betulinic acid (2) and corosolic acid (5) increased glucose transporter 4 (GLUT-4) translocation by 2.38 and 1.78-fold, respectively.Entities:
Keywords: Antidiabetic; Eucalyptus citriodora; GLUT-4; Triketone–dihydrochalcone conjugate; Triterpenes
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Year: 2014 PMID: 24894556 DOI: 10.1016/j.bmcl.2014.05.014
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823