Literature DB >> 24893194

Achondroplasia among ancient populations of mesoamerica and South America: Iconographic and Archaeological Evidence.

Carlos A Rodríguez1, Carolina Isaza2, Harry Pachajoa3.   

Abstract

INTRODUCTION: Achondroplasia is the most frequent form of short-limb dwarfism. Affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, genu varum, and trident hand. Although the etiology of this disease was reported in 1994, evidence of this disease in ancient populations has been found in populations of ancient Egypt (2500 BC) and it has been documented in ancient American populations.
OBJECTIVE: To analyze the presence of individuals with achondroplasia in the Mayan state society of Mexico and Guatemala, during the Classical (100- 950 AC ) and Post-Classical (950 - 1519 AC ) periods; likewise, in the hierarchical-chieftain society of Tumaco-la Tolita (300 BC - 600 AC ) from the Colombia-Ecuador Pacific coast, and the Moche state society (100 - 600 AC ) from the northern coast of Peru.
METHODS: Iconographic and clinical-morphological studies of some of the most important artistic representations of individuals of short stature in these three cultures.
CONCLUSION: We present the hypothesis that the individuals with short stature were somehow associated with the political and religious power elite.

Entities:  

Keywords:  Achondroplasia; archaeology; dwarfism; genetics

Year:  2012        PMID: 24893194      PMCID: PMC4001954     

Source DB:  PubMed          Journal:  Colomb Med (Cali)        ISSN: 0120-8322


  7 in total

1.  [Possible case of Morquio syndrome in the pottery of Tumaco-Tolita culture].

Authors:  H Pachajoa; C A Rodríguez; C Isaza
Journal:  Rev Neurol       Date:  2009 Jan 1-15       Impact factor: 0.870

2.  Genetic and other diseases in the pottery of Tumaco-La Tolita culture in Colombia-Ecuador.

Authors:  J E Bernal; I Briceno
Journal:  Clin Genet       Date:  2006-09       Impact factor: 4.438

3.  [Hemifacial microsomia (oculo-auriculo-vertebral spectrum) in Pre-Hispanic Tumaco-La Tolita ceramic culture (300 b.C. to 600 a.C.)].

Authors:  H Pachajoa; C A Rodríguez; C Isaza
Journal:  Arch Soc Esp Oftalmol       Date:  2010-04

Review 4.  Dwarfs in ancient Egypt.

Authors:  Chahira Kozma
Journal:  Am J Med Genet A       Date:  2006-02-15       Impact factor: 2.802

5.  Mortality in achondroplasia study: a 42-year follow-up.

Authors:  Julia Wynn; Terri M King; Michael J Gambello; D Kim Waller; Jacqueline T Hecht
Journal:  Am J Med Genet A       Date:  2007-11-01       Impact factor: 2.802

6.  The gene for achondroplasia maps to the telomeric region of chromosome 4p.

Authors:  M Velinov; S A Slaugenhaupt; I Stoilov; C I Scott; J F Gusella; P Tsipouras
Journal:  Nat Genet       Date:  1994-03       Impact factor: 38.330

7.  Skeletal dysplasia in ancient Egypt.

Authors:  Chahira Kozma
Journal:  Am J Med Genet A       Date:  2008-12-01       Impact factor: 2.802

  7 in total
  2 in total

1.  Myxoedema in a patient with achondroplasia in rural area of Guatemala.

Authors:  Michel Juarez; Peter Rohloff
Journal:  BMJ Case Rep       Date:  2017-03-09

2.  Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome) in the pre-Columbian culture of Colombia.

Authors:  Harry Pachajoa; Carlos Armando Rodriguez
Journal:  Colomb Med (Cali)       Date:  2014-06-30
  2 in total

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