Literature DB >> 24890837

Mendelian genetics of human susceptibility to fungal infection.

Michail S Lionakis1, Mihai G Netea2, Steven M Holland3.   

Abstract

A recent surge in newly described inborn errors of immune function-related genes that result in susceptibility to fungal disease has greatly enhanced our understanding of the cellular and molecular basis of antifungal immune responses. Characterization of single-gene defects that predispose to various combinations of superficial and deep-seated infections caused by yeasts, molds, and dimorphic fungi has unmasked the critical role of novel molecules and signaling pathways in mucosal and systemic antifungal host defense. These experiments of nature offer a unique opportunity for developing new knowledge in immunological research and form the foundation for devising immune-based therapeutic approaches for patients infected with fungal pathogens.
Copyright © 2014 Cold Spring Harbor Laboratory Press; all rights reserved.

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Year:  2014        PMID： 24890837      PMCID： PMC4031953          DOI： 10.1101/cshperspect.a019638

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN： 2157-1422            Impact factor:   6.915


  119 in total

1.  Continuous G-CSF therapy for isolated chronic mucocutaneous candidiasis: complete clinical remission with restoration of IL-17 secretion.

Authors:  Gizi Wildbaum; Eduardo Shahar; Rina Katz; Nathan Karin; Amos Etzioni; Shimon Pollack
Journal:  J Allergy Clin Immunol       Date:  2013-06-20       Impact factor: 10.793

2.  Killing activity of neutrophils is mediated through activation of proteases by K+ flux.

Authors:  Emer P Reeves; Hui Lu; Hugues Lortat Jacobs; Carlo G M Messina; Steve Bolsover; Giorgio Gabella; Eric O Potma; Alice Warley; Jürgen Roes; Anthony W Segal
Journal:  Nature       Date:  2002-03-21       Impact factor: 49.962

3.  Hereditary myeloperoxidase deficiency.

Authors:  P Cech; A Papathanassiou; G Boreux; P Roth; P A Miescher
Journal:  Blood       Date:  1979-03       Impact factor: 22.113

Review 4.  Hyper-IgE syndromes.

Authors:  Bodo Grimbacher; Steven M Holland; Jennifer M Puck
Journal:  Immunol Rev       Date:  2005-02       Impact factor: 12.988

5.  Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia.

Authors:  A Jain; C A Ma; S Liu; M Brown; J Cohen; W Strober
Journal:  Nat Immunol       Date:  2001-03       Impact factor: 25.606

6.  Genetic homogeneity of autoimmune polyglandular disease type I.

Authors:  P Björses; J Aaltonen; A Vikman; J Perheentupa; G Ben-Zion; G Chiumello; N Dahl; P Heideman; J J Hoorweg-Nijman; L Mathivon; P E Mullis; M Pohl; M Ritzen; G Romeo; M S Shapiro; C S Smith; J Solyom; J Zlotogora; L Peltonen
Journal:  Am J Hum Genet       Date:  1996-10       Impact factor: 11.025

7.  Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung.

Authors:  Anupam Jhingran; Katrina B Mar; Debra K Kumasaka; Sue E Knoblaugh; Lisa Y Ngo; Brahm H Segal; Yoichiro Iwakura; Clifford A Lowell; Jessica A Hamerman; Xin Lin; Tobias M Hohl
Journal:  Cell Rep       Date:  2012-11-29       Impact factor: 9.423

8.  Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome.

Authors:  Joshua D Milner; Jason M Brenchley; Arian Laurence; Alexandra F Freeman; Brenna J Hill; Kevin M Elias; Yuka Kanno; Christine Spalding; Houda Z Elloumi; Michelle L Paulson; Joie Davis; Amy Hsu; Ava I Asher; John O'Shea; Steven M Holland; William E Paul; Daniel C Douek
Journal:  Nature       Date:  2008-03-12       Impact factor: 49.962

9.  A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.

Authors:  Haifa H Jabara; Toshiro Ohsumi; Janet Chou; Michel J Massaad; Halli Benson; Andre Megarbane; Eliane Chouery; Raymond Mikhael; Oliver Gorka; Andreas Gewies; Pierre Portales; Toshinori Nakayama; Hiroyuki Hosokawa; Patrick Revy; Henry Herrod; Francoise Le Deist; Gerard Lefranc; Jürgen Ruland; Raif S Geha
Journal:  J Allergy Clin Immunol       Date:  2013-05-31       Impact factor: 10.793

10.  Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.

Authors:  Rachel Emma Dickinson; Helen Griffin; Venetia Bigley; Louise N Reynard; Rafiqul Hussain; Muzlifah Haniffa; Jeremy H Lakey; Thahira Rahman; Xiao-Nong Wang; Naomi McGovern; Sarah Pagan; Sharon Cookson; David McDonald; Ignatius Chua; Jonathan Wallis; Andrew Cant; Michael Wright; Bernard Keavney; Patrick F Chinnery; John Loughlin; Sophie Hambleton; Mauro Santibanez-Koref; Matthew Collin
Journal:  Blood       Date:  2011-07-15       Impact factor: 22.113
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  42 in total

Review 1.  Inborn errors in immunity: unique natural models to dissect oral immunity.

Authors:  N M Moutsopoulos; M S Lionakis; G Hajishengallis
Journal:  J Dent Res       Date:  2015-04-21       Impact factor: 6.116

Review 2.  Immune responses to invasive aspergillosis: new understanding and therapeutic opportunities.

Authors:  Tobias M Hohl
Journal:  Curr Opin Infect Dis       Date:  2017-08       Impact factor: 4.915

3.  Human invasive mycoses: immunogenetics on the rise.

Authors:  Michail S Lionakis; Steven M Holland
Journal:  J Infect Dis       Date:  2014-07-23       Impact factor: 5.226

Review 4.  Organ-specific mechanisms linking innate and adaptive antifungal immunity.

Authors:  Rebecca A Drummond; Michail S Lionakis
Journal:  Semin Cell Dev Biol       Date:  2018-02-01       Impact factor: 7.727

5.  Understanding the role of host immune responses in invasive candidiasis.

Authors:  Jigar V Desai; Frank L van de Veerdonk; Michail S Lionakis
Journal:  Intensive Care Med       Date:  2017-11-22       Impact factor: 17.440

6.  Unique Tailoring of Th17 at the Gingival Oral Mucosal Barrier.

Authors:  J E Konkel; N M Moutsopoulos
Journal:  J Dent Res       Date:  2017-10-13       Impact factor: 6.116

Review 7.  Tissue-Specific Immunity at the Oral Mucosal Barrier.

Authors:  Niki M Moutsopoulos; Joanne E Konkel
Journal:  Trends Immunol       Date:  2017-09-08       Impact factor: 16.687

Review 8.  Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies.

Authors:  Kathleen E Sullivan; Hamid Bassiri; Ahmed A Bousfiha; Beatriz T Costa-Carvalho; Alexandra F Freeman; David Hagin; Yu L Lau; Michail S Lionakis; Ileana Moreira; Jorge A Pinto; M Isabel de Moraes-Pinto; Amit Rawat; Shereen M Reda; Saul Oswaldo Lugo Reyes; Mikko Seppänen; Mimi L K Tang
Journal:  J Clin Immunol       Date:  2017-08-07       Impact factor: 8.317

9.  Extrapulmonary Aspergillus infection in patients with CARD9 deficiency.

Authors:  Nikolaus Rieber; Roel P Gazendam; Alexandra F Freeman; Amy P Hsu; Amanda L Collar; Janyce A Sugui; Rebecca A Drummond; Chokechai Rongkavilit; Kevin Hoffman; Carolyn Henderson; Lily Clark; Markus Mezger; Muthulekha Swamydas; Maik Engeholm; Rebecca Schüle; Bettina Neumayer; Frank Ebel; Constantinos M Mikelis; Stefania Pittaluga; Vinod K Prasad; Anurag Singh; Joshua D Milner; Kelli W Williams; Jean K Lim; Kyung J Kwon-Chung; Steven M Holland; Dominik Hartl; Taco W Kuijpers; Michail S Lionakis
Journal:  JCI Insight       Date:  2016-10-20

Review 10.  A role for airway taste receptor modulation in the treatment of upper respiratory infections.

Authors:  Jennifer E Douglas; Cecil J Saunders; Danielle R Reed; Noam A Cohen
Journal:  Expert Rev Respir Med       Date:  2016-01-22       Impact factor: 3.772
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