Literature DB >> 24890095

Selection of a right posterior sector graft for living donor liver transplantation.

Tomoharu Yoshizumi1, Toru Ikegami, Koichi Kimura, Hideaki Uchiyama, Tetsuo Ikeda, Ken Shirabe, Yoshihiko Maehara.   

Abstract

Right posterior sector (RPS) grafts have been used to overcome graft size discrepancies, the major concern of living donor liver transplantation. Previous studies have reported the volumetry-based selection of RPS grafts without anatomical exclusion. We reviewed our data and established selection criteria for RPS grafts. The procurement of RPS grafts [conventional (n = 3) and extended (n = 5)] was performed for 8 of 429 recipients at our center. Extended RPS grafts contained the drainage area of the right hepatic vein. The mean graft weight (GW) according to 3-dimensional computed tomography volumetry was 488 g, and the GW/standard liver weight (SLW) ratio was 42.6%. The mean actual GW was 437 g, and the GW/SLW ratio was 38.4%. One donor exhibited standard bifurcation of the right portal vein (PV) and the left PV, and 2 donors exhibited trifurcation of the left PV, the right anterior portal vein (APV), and the posterior PV. The remaining 5 donors exhibited APV branching from the left PV, which is the most suitable anatomy for RPS grafts. Two recipients died of sepsis or small-for-size graft syndrome. One underwent retransplantation because of an intractable bile leak and fibrosing cholestatic hepatitis. Intractable bile duct (BD) stenosis developed in 4 of the 6 survivors. In conclusion, with the significant complications and potential concerns associated with RPS grafts, these grafts should be used very rarely and with extreme caution. Donors with the standard bifurcation of the PV and the posterior BD running through the dorsal side of the posterior PV are not suitable candidates for RPS grafts. Extended RPS graft procurement is recommended for easier parenchymal transection.
© 2014 American Association for the Study of Liver Diseases.

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Year:  2014        PMID: 24890095     DOI: 10.1002/lt.23924

Source DB:  PubMed          Journal:  Liver Transpl        ISSN: 1527-6465            Impact factor:   5.799


  5 in total

1.  Predictor of outcome after living donor liver transplantation for patients with hepatocellular carcinoma beyond the Japan criteria.

Authors:  Yusuke Yonemura; Tomoharu Yoshizumi; Shoichi Inokuchi; Yukiko Kosai-Fujimoto; Noboru Harada; Shinji Itoh; Takeo Toshima; Kazuki Takeishi; Shohei Yoshiya; Masaki Mori
Journal:  Ann Gastroenterol Surg       Date:  2020-04-24

2.  Hemophagocytic syndrome after living donor liver transplantation: a case report with a review of the literature.

Authors:  Norifumi Iseda; Tomoharu Yoshizumi; Takeo Toshima; Akinari Morinaga; Takahiro Tomiyama; Junichi Takahashi; Takashi Motomura; Yohei Mano; Shinji Itoh; Noboru Harada; Toru Ikegami; Yuji Soejima
Journal:  Surg Case Rep       Date:  2018-08-29

Review 3.  Portal flow modulation in living donor liver transplantation: review with a focus on splenectomy.

Authors:  Tomoharu Yoshizumi; Masaki Mori
Journal:  Surg Today       Date:  2019-09-25       Impact factor: 2.549

4.  Up-regulated LRRN2 expression as a marker for graft quality in living donor liver transplantation.

Authors:  Takahiro Tomiyama; Takuya Yamamoto; Shokichi Takahama; Takeo Toshima; Shinji Itoh; Noboru Harada; Mototsugu Shimokawa; Daisuke Okuzaki; Masaki Mori; Tomoharu Yoshizumi
Journal:  Hepatol Commun       Date:  2022-07-27

5.  Which is better to use "body weight" or "standard liver weight", for predicting small-for-size graft syndrome after living donor liver transplantation?

Authors:  Takeo Toshima; Tomoharu Yoshizumi; Tomonari Shimagaki; Huanlin Wang; Takeshi Kurihara; Yoshihiro Nagao; Shinji Itoh; Noboru Harada; Masaki Mori
Journal:  Ann Gastroenterol Surg       Date:  2020-12-11
  5 in total

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