Literature DB >> 24889156

Absence of maternal cell contamination in mesenchymal stromal cell cultures derived from equine umbilical cord tissue.

I Vackova1, V Czernekova2, M Tomanek3, J Navratil4, T Mosko5, Z Novakova3.   

Abstract

This study aimed to determine whether maternal cell contamination exists in cells derived from equine umbilical cord tissue, a perspective material for cell-based therapies in veterinary medicine. Potential maternal cell contamination was analyzed at DNA level via a set of 16 microsatellite markers in cells originating from the cord tissue of 22 foals. In these cells no maternal cell contamination was detected at a sensitivity level of 0.01%. Our results suggest that equine umbilical cord tissue-derived cells are entirely of fetal origin.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Maternal cell contamination; Mesenchymal stromal cells; Microsatellite markers; Umbilical cord tissue

Mesh：

Year:  2014        PMID： 24889156     DOI： 10.1016/j.placenta.2014.04.005

Source DB:  PubMed          Journal:  Placenta        ISSN： 0143-4004            Impact factor:   3.481


  1 in total

1.  The Effect of Wharton Jelly-Derived Mesenchymal Stromal Cells and Their Conditioned Media in the Treatment of a Rat Spinal Cord Injury.

Authors:  Milada Chudickova; Irena Vackova; Lucia Machova Urdzikova; Pavlina Jancova; Kristyna Kekulova; Monika Rehorova; Karolina Turnovcova; Pavla Jendelova; Sarka Kubinova
Journal:  Int J Mol Sci       Date:  2019-09-12       Impact factor: 5.923
  1 in total

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