| Literature DB >> 24885413 |
Murat Işık1, Ruslan Guliyev, Safacan Kolemen, Yigit Altay, Berna Senturk, Turgay Tekinay, Engin U Akkaya.
Abstract
A selective probe for glutathione was designed and synthesized. The design incorporates spatial and photophysical constraints for the maximal emission signal. Thus, pHs, as well as the intracellular thiol concentrations, determine the emission signal intensity through a tight control of charge-transfer and PeT processes. The probe works satisfactorily inside the human breast adenocarcinoma cells, highlighting GSH distribution in the cytosol.Entities:
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Year: 2014 PMID： 24885413 DOI： 10.1021/ol501272z
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005