Literature DB >> 24882713

A fluorescent probe for imaging symmetric and asymmetric cell division in neurosphere formation.

Seong-Wook Yun1, Cheryl Leong, Xuezhi Bi, Hyung-Ho Ha, Yuan Hong Yu, Yee Ling Tan, Gunaseelan Narayanan, Shvetha Sankaran, Jun-Young Kim, Srivats Hariharan, Sohail Ahmed, Young-Tae Chang.   

Abstract

We report here a novel fluorescent chemical probe which stains distinct neural stem/progenitor cells (NSPCs) by binding to acid ceramidase in mouse neurospheres. is distributed evenly or unevenly to the daughter cells during multiple mitoses enabling the live imaging of symmetric and asymmetric divisions of isolated NSPCs.

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Year:  2014        PMID: 24882713     DOI: 10.1039/c4cc02974g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library.

Authors:  Naoki Miyamoto; Young-Hyun Go; Larissa Miasiro Ciaramicoli; Haw-Young Kwon; Heon Seok Kim; Xuezhi Bi; Young Hyun Yu; Beomsue Kim; Hyung-Ho Ha; Nam-Young Kang; Seong-Wook Yun; Jin-Soo Kim; Hyuk-Jin Cha; Young-Tae Chang
Journal:  RSC Chem Biol       Date:  2021-08-20
  1 in total

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