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Literature DB >> 24882618

MicroRNA and gynecological reproductive diseases.

Abstract

MicroRNAs (miRNAs) are a class of small non-coding RNAs estimated to regulate the translation of mRNAs in 30% of all genes in animals by inhibiting translation. Aberrant miRNA expression is associated with many human diseases, including gynecological diseases, cancer, inflammatory diseases, and cardiovascular disorders. Abnormal expression of miRNAs has been observed in multiple human reproductive tract diseases including preeclampsia, endometrioid endometrial adenocarcinoma, uterine leiomyomata, ovarian carcinoma, endometriosis, and recurrent pregnancy loss. In the following review, an update of the role of microRNA and gynecological diseases is performed covering, not only impact of microRNA dysregulation in the origin of each disease, but also showing the potential useful diagnostic and therapeutic tool that miRNA may play in these gynecological pathologies.

Entities: Disease Species

Keywords: MicroRNA; endometriosis; leiomyoma; ovarian endometriosis; peritoneal endometriosis; recurrent pregnancy loss; single nucleotide polymorphisms

Mesh：

Substances：
Genetic Markers
MicroRNAs

Year: 2014 PMID： 24882618 DOI： 10.1016/j.fertnstert.2014.04.044

Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329

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Cited

49 in total

1. Endometriosis Located Proximal to or Remote From the Uterus Differentially Affects Uterine Gene Expression.

Authors: Hanyia Naqvi; Ramanaiah Mamillapalli; Graciela Krikun; Hugh S Taylor
Journal: Reprod Sci Date: 2015-10-28 Impact factor: 3.060

2. Evaluation of miR-135a/b expression in endometriosis lesions.

Authors: Rafaella Petracco; Ana Cristina De Oliveira Dias; Hugh Taylor; Álvaro Petracco; Mariângela Badalotti; João Da Rosa Michelon; Daniel Rodrigo Marinowic; Marta Hentschke; Pamella Nunes De Azevedo; Gabriele Zanirati; Denise Cantarelli Machado
Journal: Biomed Rep Date: 2019-09-02

Review 3. Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders.

Authors: Virginie Gillet; Darel John Hunting; Larissa Takser
Journal: Curr Environ Health Rep Date: 2016-09

4. Association between miR-146a C > G, miR-149 T > C, miR-196a2 T > C, and miR-499 A > G polymorphisms and susceptibility to idiopathic recurrent pregnancy loss.

Authors: Meysam Alipour; Maryam Abtin; Asghar Hosseinzadeh; Masoud Maleki
Journal: J Assist Reprod Genet Date: 2019-10-11 Impact factor: 3.412

MicroRNA and gynecological reproductive diseases.

1. Endometriosis Located Proximal to or Remote From the Uterus Differentially Affects Uterine Gene Expression.

2. Evaluation of miR-135a/b expression in endometriosis lesions.

Review 3. Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders.

4. Association between miR-146a C > G, miR-149 T > C, miR-196a2 T > C, and miR-499 A > G polymorphisms and susceptibility to idiopathic recurrent pregnancy loss.

5. Endometrial Stromal and Epithelial Cells Exhibit Unique Aberrant Molecular Defects in Patients With Endometriosis.

6. Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis.

7. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis.

8. miR-200 Regulates Endometrial Development During Early Pregnancy.

Review 9. MicroRNAs in endometriosis: biological function and emerging biomarker candidates†.

Review 10. The role of miRNAs in regulating adrenal and gonadal steroidogenesis.