Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Are we done monkeying around with TRIM5α?

Literature DB >> 24881765

Are we done monkeying around with TRIM5α?

Edward Campbell¹.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2014 PMID： 24881765 PMCID： PMC4048908 DOI： 10.1038/mt.2014.74

Source DB: PubMed Journal: Mol Ther ISSN： 1525-0016 Impact factor: 11.454

Keyword Cloud
References

× No keyword cloud information.

8 in total

1. Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection.

Authors: Xiaolu Wu; Jenny L Anderson; Edward M Campbell; Ajith M Joseph; Thomas J Hope
Journal: Proc Natl Acad Sci U S A Date: 2006-04-28 Impact factor: 11.205

2. Identification of residues within the L2 region of rhesus TRIM5alpha that are required for retroviral restriction and cytoplasmic body localization.

Authors: Jaya Sastri; Christopher O'Connor; Cindy M Danielson; Michael McRaven; Patricio Perez; Felipe Diaz-Griffero; Edward M Campbell
Journal: Virology Date: 2010-07-14 Impact factor: 3.616

Review 3. Molecular evolution of the antiretroviral TRIM5 gene.

Authors: Welkin E Johnson; Sara L Sawyer
Journal: Immunogenetics Date: 2009-02-24 Impact factor: 2.846

4. A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.

Authors: Felipe Diaz-Griffero; Xu-rong Qin; Fumiaki Hayashi; Takanori Kigawa; Andres Finzi; Zoe Sarnak; Maritza Lienlaf; Shigeyuki Yokoyama; Joseph Sodroski
Journal: J Virol Date: 2009-08-05 Impact factor: 5.103

Are we done monkeying around with TRIM5α?

1. Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection.

2. Identification of residues within the L2 region of rhesus TRIM5alpha that are required for retroviral restriction and cytoplasmic body localization.

Review 3. Molecular evolution of the antiretroviral TRIM5 gene.

4. A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.

5. Stabilized human TRIM5α protects human T cells from HIV-1 infection.

6. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.

7. A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction.

8. Proteasomal degradation of TRIM5alpha during retrovirus restriction.