Literature DB >> 24880948

Interferon, interleukin-2, and other cytokines.

Elizabeth I Buchbinder1, David F McDermott2.   

Abstract

Cytokines are a diverse group of signaling molecules with immunomodulatory activity. This article reviews the application of cytokine therapy in melanoma with a focus on interferon-α and interleukin-2. In addition, it addresses the clinical considerations of these therapies including patient selection, reduction in toxicity, and combination regimens.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cytokines; Granulocyte-macrophage colony–stimulating factor; Interferon; Interleukin-2; Interleukin-21; Melanoma

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Year:  2014        PMID： 24880948     DOI： 10.1016/j.hoc.2014.02.001

Source DB:  PubMed          Journal:  Hematol Oncol Clin North Am        ISSN： 0889-8588            Impact factor:   3.722


  3 in total

1.  Anti-VEGFR2-interferon-α2 regulates the tumor microenvironment and exhibits potent antitumor efficacy against colorectal cancer.

Authors:  Zhaoting Li; Yijia Zhu; Chenchen Li; Ryan Trinh; Xueyan Ren; Fumou Sun; Youfu Wang; Pengzhao Shang; Tong Wang; Min Wang; Sherie L Morrison; Juan Zhang
Journal:  Oncoimmunology       Date:  2017-02-17       Impact factor: 8.110

2.  VEGFR2-targeted antibody fused with IFN α mut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis activity.

Authors:  Pengzhao Shang; Rui Gao; Yijia Zhu; Xiaorui Zhang; Yang Wang; Minji Guo; Hui Peng; Min Wang; Juan Zhang
Journal:  Acta Pharm Sin B       Date:  2020-09-19       Impact factor: 11.413

Review 3.  The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs).

Authors:  Payam Behzadi; Aga Syed Sameer; Saniya Nissar; Mujeeb Zafar Banday; Márió Gajdács; Herney Andrés García-Perdomo; Kulsum Akhtar; Marina Pinheiro; Peter Magnusson; Meysam Sarshar; Cecilia Ambrosi
Journal:  J Immunol Res       Date:  2022-03-26       Impact factor: 4.818
  3 in total

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