Literature DB >> 24880696

Postoperative delirium and pre-fracture disability predict 6-month mortality among the oldest old hip fracture patients.

Paolo Mazzola1, Giuseppe Bellelli, Valentina Broggini, Alessandra Anzuini, Maurizio Corsi, Daniele Berruti, Francesco De Filippi, Giovanni Zatti, Giorgio Annoni.   

Abstract

BACKGROUND: Age is one of the most robust risk factors for hip fracture. Recent projections indicate that almost half of hip fractures are occurring with an increasing trend among the "oldest old" (i.e., in those aged >85 years). AIMS: To compare clinical characteristics, outcomes, and risk factors for 6-month mortality in two groups of "oldest old" patients (group 1 = 85-89, group 2 > 90 years), after hip fracture surgery.
METHODS: Observational prospective cohort study with 6-month follow-up, performed in an Orthogeriatric Unit of an academic hospital between March 2007 and November 2012.
RESULTS: Two hundred seventy-five patients (group 1: N = 171; group 2: N = 104) underwent a comprehensive geriatric assessment, including demographics, clinical, functional, nutritional, and mental status. The 6-month rehospitalization and mortality rates after surgery were assessed through structured telephone interviews with patient's caregivers. Multivariate logistic regression models were used to evaluate predictors of 6-month mortality, adjusting for relevant covariates. Fifty-eight patients died at follow-up. The in-hospital and 6-month mortality rates were significantly higher for patients of group 2 than for those of group 1. After adjusting for covariates, the multivariate logistic regressions showed that severe disability (OR 2.24, 95 % CI 1.08-4.65) and postoperative delirium (POD) (OR 3.80, 95 % CI 1.72-8.39) were predictors of 6-month mortality.
CONCLUSIONS: Patients aged >90 years who underwent hip fracture surgery are more likely to die at 6 months than those aged 85-89 years. Pre-fracture disability and POD are predictors of this excess of mortality.

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Year:  2014        PMID: 24880696     DOI: 10.1007/s40520-014-0242-y

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  12 in total

1.  Prolonged hospital stay before hip fracture surgery in the elderly: a single parameter but multiple roles.

Authors:  Paolo Mazzola
Journal:  Int Orthop       Date:  2017-11-21       Impact factor: 3.075

2.  Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials.

Authors:  Xia Li; Yanting Wang; Jie Liu; Yue Xiong; Shiqiang Chen; Jingjing Han; Wanli Xie; Qingping Wu
Journal:  Medicine (Baltimore)       Date:  2021-07-23       Impact factor: 1.817

3.  [Clinical study of recombinant human erythropoietin combined with iron to correct perioperative anemia in elderly patients with intertrochanteric fractures].

Authors:  Ye Long; Tong Wang; Jiaxin Liu; Xin Duan; Zhou Xiang
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-06-15

4.  The increase of osteopontin and β-carboxy-terminal cross-linking telopeptide of type I collagen enhances the risk of hip fracture in the elderly.

Authors:  Jian-Chun Lin; Zhong-Guo Liu; Rui-Ren Liu; Liang-Wen Xie; Huang-Lin Xie; He-Guo Cai
Journal:  J Clin Lab Anal       Date:  2020-05-14       Impact factor: 2.352

5.  Association of Geriatric Comanagement and 90-Day Postoperative Mortality Among Patients Aged 75 Years and Older With Cancer.

Authors:  Armin Shahrokni; Amy L Tin; Saman Sarraf; Koshy Alexander; Steve Sun; Soo Jung Kim; Sincere McMillan; Heidi Yulico; Farnia Amirnia; Robert J Downey; Andrew J Vickers; Beatriz Korc-Grodzicki
Journal:  JAMA Netw Open       Date:  2020-08-03

6.  Risk factors associated with outcomes of hip fracture surgery in elderly patients.

Authors:  Byung Hoon Kim; Sangseok Lee; Byunghoon Yoo; Woo Yong Lee; Yunhee Lim; Mun-Cheol Kim; Jun Heum Yon; Kye-Min Kim
Journal:  Korean J Anesthesiol       Date:  2015-11-25

Review 7.  Orthogeriatric care: improving patient outcomes.

Authors:  Francisco José Tarazona-Santabalbina; Ángel Belenguer-Varea; Eduardo Rovira; David Cuesta-Peredó
Journal:  Clin Interv Aging       Date:  2016-06-24       Impact factor: 4.458

8.  Early postoperative delirium after hemiarthroplasty in elderly patients aged over 70 years with displaced femoral neck fracture.

Authors:  Yi-Hwa Choi; Dae-Hwan Kim; Tae-Young Kim; Tae-Wan Lim; Seok-Woo Kim; Je-Hyun Yoo
Journal:  Clin Interv Aging       Date:  2017-11-06       Impact factor: 4.458

9.  A call to action for delirium research: Meta-analysis and regression of delirium associated mortality.

Authors:  May Zin Aung Thein; Jarett V Pereira; Anita Nitchingham; Gideon A Caplan
Journal:  BMC Geriatr       Date:  2020-09-07       Impact factor: 3.921

10.  Caregivers' misperception of the severity of hip fractures.

Authors:  Sara Elli; Diego Contro; Silvana Castaldi; Marco Fornili; Ilaria Ardoino; Antonello V Caserta; Lorenzo Panella
Journal:  Patient Prefer Adherence       Date:  2018-09-21       Impact factor: 2.711

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