Literature DB >> 24880104

Cellular and molecular mechanisms of cartilage damage and repair.

Joanna C Sherwood1, Jessica Bertrand1, Suzanne E Eldridge1, Francesco Dell'Accio2.   

Abstract

Cartilage breakdown is the disabling outcome of rheumatic diseases, whether prevalently inflammatory such as rheumatoid arthritis or prevalently mechanical such as osteoarthritis (OA). Despite the differences between immune-mediated arthritides and OA, common mechanisms drive cartilage breakdown. Inflammation, chondrocyte phenotype and homeostatic mechanisms have recently been the focus of research and will be summarised in this review.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID： 24880104     DOI： 10.1016/j.drudis.2014.05.014

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  16 in total

1.  Quantitative SHG imaging in osteoarthritis model mice, implying a diagnostic application.

Authors:  Hiroshi Kiyomatsu; Yusuke Oshima; Takashi Saitou; Tsuyoshi Miyazaki; Atsuhiko Hikita; Hiromasa Miura; Tadahiro Iimura; Takeshi Imamura
Journal:  Biomed Opt Express       Date:  2015-01-08       Impact factor: 3.732

Review 2.  Cellular and molecular pathways of structural damage in rheumatoid arthritis.

Authors:  Ulrike Harre; Georg Schett
Journal:  Semin Immunopathol       Date:  2017-06-08       Impact factor: 9.623

Review 3.  In vivo potency assay for the screening of bioactive molecules on cartilage formation.

Authors:  Anne-Sophie Thorup; Sara Caxaria; Bethan L Thomas; Yasir Suleman; Giovanna Nalesso; Frank P Luyten; Francesco Dell'Accio; Suzanne E Eldridge
Journal:  Lab Anim (NY)       Date:  2022-03-31       Impact factor: 9.667

4.  WNT3A-loaded exosomes enable cartilage repair.

Authors:  Bethan L Thomas; Suzanne E Eldridge; Babak Nosrati; Mario Alvarez; Anne-Sophie Thorup; Giovanna Nalesso; Sara Caxaria; Aida Barawi; James G Nicholson; Mauro Perretti; Carles Gaston-Massuet; Costantino Pitzalis; Alison Maloney; Adrian Moore; Ray Jupp; Francesco Dell'Accio
Journal:  J Extracell Vesicles       Date:  2021-05-19

5.  CircTMOD3 promotes lipopolysaccharide-induced chondrocyte apoptosis in osteoarthritis by sponging miR-27a.

Authors:  Lu Yu; Xiaogang Zhang; Xingchao Liu; Gang Li; Mingliang Chen; Zexin Liu; Qinghe Liu
Journal:  J Bone Miner Metab       Date:  2022-02-01       Impact factor: 2.626

6.  Systemic inhibition or global deletion of CaMKK2 protects against post-traumatic osteoarthritis.

Authors:  E Mével; J A Shutter; X Ding; B T Mattingly; J N Williams; Y Li; A Huls; A V Kambrath; S B Trippel; D Wagner; M R Allen; R O'Keefe; W R Thompson; D B Burr; U Sankar
Journal:  Osteoarthritis Cartilage       Date:  2021-09-17       Impact factor: 6.576

7.  Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo.

Authors:  Suzanne Eldridge; Giovanna Nalesso; Habib Ismail; Karin Vicente-Greco; Panos Kabouridis; Manoj Ramachandran; Andreas Niemeier; Joachim Herz; Costantino Pitzalis; Mauro Perretti; Francesco Dell'Accio
Journal:  Ann Rheum Dis       Date:  2015-08-19       Impact factor: 19.103

Review 8.  Advances and Prospects in Stem Cells for Cartilage Regeneration.

Authors:  Mingjie Wang; Zhiguo Yuan; Ning Ma; Chunxiang Hao; Weimin Guo; Gengyi Zou; Yu Zhang; Mingxue Chen; Shuang Gao; Jiang Peng; Aiyuan Wang; Yu Wang; Xiang Sui; Wenjing Xu; Shibi Lu; Shuyun Liu; Quanyi Guo
Journal:  Stem Cells Int       Date:  2017-01-26       Impact factor: 5.443

9.  What is the role of erythropoietin prolotherapy on pain relief of knee osteoarthritis?

Authors:  Pooya Derakhshan
Journal:  J Res Med Sci       Date:  2018-06-06       Impact factor: 1.852

10.  The Functions of BMP3 in Rabbit Articular Cartilage Repair.

Authors:  Zhe Zhang; Wenyu Yang; Yiting Cao; Yanping Shi; Chen Lei; Bo Du; Xuemin Li; Qiqing Zhang
Journal:  Int J Mol Sci       Date:  2015-10-29       Impact factor: 5.923
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