BACKGROUND: Although hemorrhagic complications are major complications of percutaneous renal biopsy (PRB), the relationship between procedure volume and morbidity remains unclear for PRB. The present study investigated the impact of hospital volume on the occurrence of hemorrhagic complications after PRB. METHODS: Using large claims-based data in the diagnosis procedure combination database in Japan, we identified inpatients with renal disorders who underwent PRB within 4 days after admission during July to December 2007 to 2010. We assessed patient age, sex, clinical syndromes, hemorrhagic complications and diagnoses, and annual hospital volume of PRB divided into quintiles. Multivariate logistic regression analyses fitted with a generalized estimation equation were performed accounting for within-hospital clustering. RESULTS: A total of 15,191 patients were identified from 942 hospitals. The overall proportion of hemorrhagic complications was 2.1 %, including diagnoses of hemorrhagic events (1.6 %), red blood cell transfusion (0.5 %), and requiring angiography or endovascular procedure (0.1 %). In-hospital deaths attributable to the complications occurred in 0.06 % of the patients. Patients with rapidly progressive nephritic syndrome (odds ratio 3.41, 95 % confidence interval 2.22-5.25) had significantly higher incidence than those with chronic nephritic syndrome. No significant association was observed between hospital volume and hemorrhagic complications, with odds ratios for the low-intermediate, intermediate, intermediate-high, and high-volume groups relative to the low-volume group of 0.74 (0.43-1.26), 1.19 (0.74-1.92), 1.16 (0.67-2.00), and 1.35 (0.78-2.34), respectively. CONCLUSIONS: No significant relationship was observed between hemorrhagic complication incidence and hospital volume regarding PRB.
BACKGROUND: Although hemorrhagic complications are major complications of percutaneous renal biopsy (PRB), the relationship between procedure volume and morbidity remains unclear for PRB. The present study investigated the impact of hospital volume on the occurrence of hemorrhagic complications after PRB. METHODS: Using large claims-based data in the diagnosis procedure combination database in Japan, we identified inpatients with renal disorders who underwent PRB within 4 days after admission during July to December 2007 to 2010. We assessed patient age, sex, clinical syndromes, hemorrhagic complications and diagnoses, and annual hospital volume of PRB divided into quintiles. Multivariate logistic regression analyses fitted with a generalized estimation equation were performed accounting for within-hospital clustering. RESULTS: A total of 15,191 patients were identified from 942 hospitals. The overall proportion of hemorrhagic complications was 2.1 %, including diagnoses of hemorrhagic events (1.6 %), red blood cell transfusion (0.5 %), and requiring angiography or endovascular procedure (0.1 %). In-hospital deaths attributable to the complications occurred in 0.06 % of the patients. Patients with rapidly progressive nephritic syndrome (odds ratio 3.41, 95 % confidence interval 2.22-5.25) had significantly higher incidence than those with chronic nephritic syndrome. No significant association was observed between hospital volume and hemorrhagic complications, with odds ratios for the low-intermediate, intermediate, intermediate-high, and high-volume groups relative to the low-volume group of 0.74 (0.43-1.26), 1.19 (0.74-1.92), 1.16 (0.67-2.00), and 1.35 (0.78-2.34), respectively. CONCLUSIONS: No significant relationship was observed between hemorrhagic complication incidence and hospital volume regarding PRB.
Authors: Katherine S Panageas; Deborah Schrag; A Russell Localio; E S Venkatraman; Colin B Begg Journal: Stat Med Date: 2007-04-30 Impact factor: 2.373
Authors: Richard Fish; Jennifer Pinney; Poorva Jain; Clara Addison; Chris Jones; Satish Jayawardene; John Booth; Alexander J Howie; Tareck Ghonemy; Shahista Rajabali; David Roberts; Lucy White; Sofia Khan; Matthew Morgan; Paul Cockwell; Colin A Hutchison Journal: Clin J Am Soc Nephrol Date: 2010-07-22 Impact factor: 8.237
Authors: P Stratta; C Canavese; M Marengo; P Mesiano; L Besso; M Quaglia; D Bergamo; G Monga; G Mazzucco; G Ciccone Journal: Eur J Clin Invest Date: 2007-12 Impact factor: 4.686