Literature DB >> 24878685

Broad-spectrum antiviral property of polyoxometalate localized on a cell surface.

Juan Wang1, Yang Liu, Kun Xu, Yanfei Qi, Jun Zhong, Kai Zhang, Juan Li, Enbo Wang, Ziyu Wu, Zhenhui Kang.   

Abstract

Cs2K4Na[SiW9Nb3O40] has broad antiviral ability including anti-Influenza A, -Influenza B, -HSV-1, -HSV-2, -HIV-1, and -HBV. A series of antivirus and/or biochemical experiments and X-ray nanotomography analysis confirm that this kind of broad-spectrum antiviral property is mainly due to its localization on the cell surface.

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Year:  2014        PMID： 24878685     DOI： 10.1021/am502193f

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN： 1944-8244            Impact factor:   9.229


  10 in total

1.  In vitro and in vivo antifungal activities and mechanism of heteropolytungstates against Candida species.

Authors:  Han Li; Hongwei Gong; Yanfei Qi; Juan Li; Xufeng Ji; Jiaheng Sun; Rui Tian; Hao Bao; Xiangfu Song; Qiang Chen; Guoliang Liu
Journal:  Sci Rep       Date:  2017-12-05       Impact factor: 4.379

2.  Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats.

Authors:  Xiaofeng Qu; Kun Xu; Chao Zhao; Xiuling Song; Jinhua Li; Li Li; Wei Nie; Hao Bao; Juan Wang; Fenglan Niu; Juan Li
Journal:  BMC Pharmacol Toxicol       Date:  2017-04-05       Impact factor: 2.483

3.  Inhibition of H1N1 influenza virus-induced apoptosis by functionalized selenium nanoparticles with amantadine through ROS-mediated AKT signaling pathways.

Authors:  Yinghua Li; Zhengfang Lin; Min Guo; Mingqi Zhao; Yu Xia; Changbing Wang; Tiantian Xu; Bing Zhu
Journal:  Int J Nanomedicine       Date:  2018-04-03

4.  Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.

Authors:  Maria Gil-Moles; Sebastian Türck; Uttara Basu; Andrea Pettenuzzo; Saurav Bhattacharya; Ananthu Rajan; Xiang Ma; Rolf Büssing; Jessica Wölker; Hilke Burmeister; Henrik Hoffmeister; Pia Schneeberg; Andre Prause; Petra Lippmann; Josephine Kusi-Nimarko; Storm Hassell-Hart; Andrew McGown; Daniel Guest; Yan Lin; Anna Notaro; Robin Vinck; Johannes Karges; Kevin Cariou; Kun Peng; Xue Qin; Xing Wang; Joanna Skiba; Łukasz Szczupak; Konrad Kowalski; Ulrich Schatzschneider; Catherine Hemmert; Heinz Gornitzka; Elena R Milaeva; Alexey A Nazarov; Gilles Gasser; John Spencer; Luca Ronconi; Ulrich Kortz; Jindrich Cinatl; Denisa Bojkova; Ingo Ott
Journal:  Chemistry       Date:  2021-11-23       Impact factor: 5.020

5.  Can polyoxometalates (POMs) prevent of coronavirus 2019-nCoV cell entry? Interaction of POMs with TMPRSS2 and spike receptor domain complexed with ACE2 (ACE2-RBD): Virtual screening approaches.

Authors:  Nahid Shahabadi; Mohammad Mahdavi; Saba Zendehcheshm
Journal:  Inform Med Unlocked       Date:  2022-03-05

6.  New composition of tungsten has a broad range of antiviral activity.

Authors:  Hranush Avagyan; Anaida Mirzoyan; Ferdinand Mirzoyan; Roza Izmailyan; Sona Hakobyan; Henry Voskanyan; Zara Semerjyan; Aida Avetisyan; Hranush Arzumanyan; Elena Karalova; Liana Abroyan; Lina Hakobyan; Nane Bayramyan; Nazeli Gevorgyan; Alexander Karalyan; Zaven Karalyan
Journal:  Antivir Chem Chemother       Date:  2022 Jan-Dec

Review 7.  Promising application of polyoxometalates in the treatment of cancer, infectious diseases and Alzheimer's disease.

Authors:  Xuechen Wang; Shengnan Wei; Chao Zhao; Xin Li; Jin Jin; Xuening Shi; Zhenyue Su; Juan Li; Juan Wang
Journal:  J Biol Inorg Chem       Date:  2022-06-17       Impact factor: 3.862

Review 8.  Metallodrugs are unique: opportunities and challenges of discovery and development.

Authors:  Elizabeth J Anthony; Elizabeth M Bolitho; Hannah E Bridgewater; Oliver W L Carter; Jane M Donnelly; Cinzia Imberti; Edward C Lant; Frederik Lermyte; Russell J Needham; Marta Palau; Peter J Sadler; Huayun Shi; Fang-Xin Wang; Wen-Ying Zhang; Zijin Zhang
Journal:  Chem Sci       Date:  2020-11-12       Impact factor: 9.825

9.  Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Keggin Polyoxometalate.

Authors:  Xiaoli Wang; Jiao Wang; Wenmei Zhang; Boye Li; Ying Zhu; Qin Hu; Yishu Yang; Xiaoguang Zhang; Hong Yan; Yi Zeng
Journal:  Viruses       Date:  2018-05-16       Impact factor: 5.048

10.  Increased in vitro Anti-HIV Activity of Caffeinium-Functionalized Polyoxometalates.

Authors:  Ana G Enderle; Matteo Bosso; Rüdiger Groß; Magdalena Heiland; Mariela Bollini; María J Culzoni; Frank Kirchhoff; Jan Münch; Carsten Streb
Journal:  ChemMedChem       Date:  2021-05-26       Impact factor: 3.466
  10 in total

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