Literature DB >> 24876734

Clinicopathological utility of sialoglycoconjugates in diagnosing and treating colorectal cancer.

Yoshinori Inagaki1, Jianjun Gao1, Peipei Song1, Norihiro Kokudo1, Munehiro Nakata1, Wei Tang1.   

Abstract

Aberrant expression of glycoconjugates occurs during malignant transformation of cancer cells. Overexpression of sialoglycoconjugates in particular may play an important role in the progression, i.e., invasion or metastasis, of cancer. Various types of sialoglycoconjugates have been investigated to clarify their biological significance and clinical utility in diagnosing and treating colorectal cancer. This review focuses specifically on expression of mucin (MUC) 1 and it suggests that MUC1 with the specific structure of a sialo-oligosaccharide has biological significance in determining the metastatic potential of colorectal cancer cells and clinicopathological utility in evaluating the effectiveness of treatments and the prognosis for patients with colorectal cancer. Further studies are expected to contribute to the expanded use of cancer-associated sialoglycoconjugates in cancer diagnosis and therapy.

Entities:  

Keywords:  Colorectal cancer; Invasion; Metastasis; Mucin 1; Sialic acid; Sialoglycoconjugates

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Substances：

Year:  2014        PMID： 24876734      PMCID： PMC4033451          DOI： 10.3748/wjg.v20.i20.6123

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  105 in total

Review 1.  Serum marker KL-6/MUC1 for the diagnosis and management of interstitial pneumonitis.

Authors:  N Kohno
Journal:  J Med Invest       Date:  1999-08

2.  Clinicopathological subclassification of biliary cystic tumors: Report of 4 cases with a review of the literature.

Authors:  Suguru Yamashita; Nobutaka Tanaka; Michiro Takahashi; Shojiro Hata; Yukihiro Nomura; Kenji Ooe; Yoshio Suzuki
Journal:  Intractable Rare Dis Res       Date:  2013-05

3.  Clinical significance of subcellular localization of KL-6 mucin in primary colorectal adenocarcinoma and metastatic tissues.

Authors:  Qian Guo; Wei Tang; Yoshinori Inagaki; Yutaka Midorikawa; Norihiro Kokudo; Yasuhiko Sugawara; Munehiro Nakata; Toshiro Konishi; Hirokazu Nagawa; Masatoshi Makuuchi
Journal:  World J Gastroenterol       Date:  2006-01-07       Impact factor: 5.742

4.  Immunohistochemical analysis of sialic acid and fucose composition in human colorectal adenocarcinoma.

Authors:  J Fernández-Rodríguez; C Feijoo-Carnero; A Merino-Trigo; M Páez de la Cadena; F J Rodríguez-Berrocal; A de Carlos; M Butrón; V S Martínez-Zorzano
Journal:  Tumour Biol       Date:  2000 May-Jun

Review 5.  Regulation of the metastatic cell phenotype by sialylated glycans.

Authors:  Matthew J Schultz; Amanda F Swindall; Susan L Bellis
Journal:  Cancer Metastasis Rev       Date:  2012-12       Impact factor: 9.264

6.  Increased expression of sialyl Lewisx antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study.

Authors:  S Nakamori; M Kameyama; S Imaoka; H Furukawa; O Ishikawa; Y Sasaki; T Kabuto; T Iwanaga; Y Matsushita; T Irimura
Journal:  Cancer Res       Date:  1993-08-01       Impact factor: 12.701

7.  Des-γ-carboxy prothrombin and c-Met were concurrently and extensively expressed in hepatocellular carcinoma and associated with tumor recurrence.

Authors:  Jianjun Gao; Xiaobin Feng; Yoshinori Inagaki; Peipei Song; Norihiro Kokudo; Kiyoshi Hasegawa; Yasuhiko Sugawara; Wei Tang
Journal:  Biosci Trends       Date:  2012-08       Impact factor: 2.400

8.  Subcellular localization of KL-6 mucin in colorectal carcinoma cell lines: association with metastatic potential and cell morphology.

Authors:  Qian Guo; Wei Tang; Yoshinori Inagaki; Norihiro Kokudo; Yasuhiko Sugawara; Hirona Karako; Munehiro Nakata; Masatoshi Makuuchi
Journal:  Oncol Rep       Date:  2007-05       Impact factor: 3.906

9.  First alert for recurrence during follow-up after potentially curative resection for colorectal carcinoma: CA 19-9 should be included in surveillance programs.

Authors:  Yutaka J Kawamura; Aika Tokumitsu; Ken Mizokami; Junichi Sasaki; Shingo Tsujinaka; Fumio Konishi
Journal:  Clin Colorectal Cancer       Date:  2010-01       Impact factor: 4.481

10.  ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.

Authors:  Nuno T Marcos; Eric P Bennett; Joana Gomes; Ana Magalhaes; Catarina Gomes; Leonor David; Imran Dar; Charlotte Jeanneau; Shawn DeFrees; Dorrit Krustrup; Lotte K Vogel; Elin H Kure; Joy Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen; Ulla Mandel; Celso A Reis
Journal:  Front Biosci (Elite Ed)       Date:  2011-06-01
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  2 in total

Review 1.  MUC1: Structure, Function, and Clinic Application in Epithelial Cancers.

Authors:  Wenqing Chen; Zhu Zhang; Shiqing Zhang; Peili Zhu; Joshua Ka-Shun Ko; Ken Kin-Lam Yung
Journal:  Int J Mol Sci       Date:  2021-06-18       Impact factor: 5.923

Review 2.  Exploring the role and diversity of mucins in health and disease with special insight into non-communicable diseases.

Authors:  Santosh Kumar Behera; Ardhendu Bhusan Praharaj; Budheswar Dehury; Sapna Negi
Journal:  Glycoconj J       Date:  2015-08-04       Impact factor: 3.009
  2 in total

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